Blood transfusion-induced anaphylaxis and coronary artery spasm during general anesthesia
Anaphylactic reactions to blood transfusion can lead to life-threatening cardiovascular disruptions. We describe a case in which anaphylaxis due to blood transfusion during general anesthesia was the probable cause of coronary artery spasm. Thirty minutes after the transfusion of concentrated red bl...
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Veröffentlicht in: | Journal of anesthesia 2008, Vol.22 (4), p.457-459 |
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container_title | Journal of anesthesia |
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creator | Osugi, Toshihiro Ueki, Ryusuke Shimode, Noriko Tatara, Tsuneo Tashiro, Chikara |
description | Anaphylactic reactions to blood transfusion can lead to life-threatening cardiovascular disruptions. We describe a case in which anaphylaxis due to blood transfusion during general anesthesia was the probable cause of coronary artery spasm. Thirty minutes after the transfusion of concentrated red blood cells, the patient’s blood pressure had dropped to 70/40 mmHg and peak airway pressure had increased to 35 cmH
2
O. The ST segment of the ECG was simultaneously elevated, and the left upper arm became extensively flushed. The tryptase concentration in the patient’s plasma collected 3 h postoperatively was 13.9 μg·l
−1
(normal range, 2.1–9.0 μg·l
−1
). This case report emphasizes that anaphylactic reactions to blood transfusion can potentially lead to coronary artery spasm. |
doi_str_mv | 10.1007/s00540-008-0658-7 |
format | Article |
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2
O. The ST segment of the ECG was simultaneously elevated, and the left upper arm became extensively flushed. The tryptase concentration in the patient’s plasma collected 3 h postoperatively was 13.9 μg·l
−1
(normal range, 2.1–9.0 μg·l
−1
). This case report emphasizes that anaphylactic reactions to blood transfusion can potentially lead to coronary artery spasm.</description><identifier>ISSN: 0913-8668</identifier><identifier>EISSN: 1438-8359</identifier><identifier>DOI: 10.1007/s00540-008-0658-7</identifier><identifier>PMID: 19011789</identifier><language>eng</language><publisher>Japan: Springer Japan</publisher><subject>Aged ; Anaphylaxis - etiology ; Anesthesia, General ; Anesthesiology ; Clinical Report ; Coronary Vasospasm - etiology ; Creatine Kinase - metabolism ; Critical Care Medicine ; Emergency Medicine ; Erythrocyte Transfusion - adverse effects ; Humans ; Intensive ; Male ; Medicine ; Medicine & Public Health ; Pain Medicine ; Transfusion Reaction ; Tryptases - blood</subject><ispartof>Journal of anesthesia, 2008, Vol.22 (4), p.457-459</ispartof><rights>Japanese Society of Anesthesiologists 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-83fa9948c00d21f2edb7fc8fa9c61c3c217dee4c1564a8383e40ecc3f2c65a7b3</citedby><cites>FETCH-LOGICAL-c395t-83fa9948c00d21f2edb7fc8fa9c61c3c217dee4c1564a8383e40ecc3f2c65a7b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00540-008-0658-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00540-008-0658-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19011789$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Osugi, Toshihiro</creatorcontrib><creatorcontrib>Ueki, Ryusuke</creatorcontrib><creatorcontrib>Shimode, Noriko</creatorcontrib><creatorcontrib>Tatara, Tsuneo</creatorcontrib><creatorcontrib>Tashiro, Chikara</creatorcontrib><title>Blood transfusion-induced anaphylaxis and coronary artery spasm during general anesthesia</title><title>Journal of anesthesia</title><addtitle>J Anesth</addtitle><addtitle>J Anesth</addtitle><description>Anaphylactic reactions to blood transfusion can lead to life-threatening cardiovascular disruptions. We describe a case in which anaphylaxis due to blood transfusion during general anesthesia was the probable cause of coronary artery spasm. Thirty minutes after the transfusion of concentrated red blood cells, the patient’s blood pressure had dropped to 70/40 mmHg and peak airway pressure had increased to 35 cmH
2
O. The ST segment of the ECG was simultaneously elevated, and the left upper arm became extensively flushed. The tryptase concentration in the patient’s plasma collected 3 h postoperatively was 13.9 μg·l
−1
(normal range, 2.1–9.0 μg·l
−1
). This case report emphasizes that anaphylactic reactions to blood transfusion can potentially lead to coronary artery spasm.</description><subject>Aged</subject><subject>Anaphylaxis - etiology</subject><subject>Anesthesia, General</subject><subject>Anesthesiology</subject><subject>Clinical Report</subject><subject>Coronary Vasospasm - etiology</subject><subject>Creatine Kinase - metabolism</subject><subject>Critical Care Medicine</subject><subject>Emergency Medicine</subject><subject>Erythrocyte Transfusion - adverse effects</subject><subject>Humans</subject><subject>Intensive</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Pain Medicine</subject><subject>Transfusion Reaction</subject><subject>Tryptases - blood</subject><issn>0913-8668</issn><issn>1438-8359</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqXwA1hQJjbDOU4ce4SKL6kSCwxMlms7barEDnYi0X-Pq1RiY7qT9dzruwehawJ3BKC6jwBlARiAY2Alx9UJmpOCcsxpKU7RHAShmDPGZ-gixh0AMELoOZoRAYRUXMzR12PrvcmGoFysx9h4hxtnRm1Nppzqt_tW_TQx9SbTPninwj5TYbCpxF7FLjNjaNwm21hng2oTaOOwtbFRl-isVm20V8e6QJ_PTx_LV7x6f3lbPqywpqIc0qq1EqLgGsDkpM6tWVe15ulRM6KpzkllrC00KVmhOOXUFmC1pnWuWamqNV2g2ym3D_57TL_Lronatm1axY9RMlEJJoAmkEygDj7GYGvZh6ZLB0kC8uBTTj5l8ikPPmWVZm6O4eO6s-Zv4igwAfkExP7gwQa582Nw6eB_Un8BSKWCxQ</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>Osugi, Toshihiro</creator><creator>Ueki, Ryusuke</creator><creator>Shimode, Noriko</creator><creator>Tatara, Tsuneo</creator><creator>Tashiro, Chikara</creator><general>Springer Japan</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2008</creationdate><title>Blood transfusion-induced anaphylaxis and coronary artery spasm during general anesthesia</title><author>Osugi, Toshihiro ; Ueki, Ryusuke ; Shimode, Noriko ; Tatara, Tsuneo ; Tashiro, Chikara</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-83fa9948c00d21f2edb7fc8fa9c61c3c217dee4c1564a8383e40ecc3f2c65a7b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Anaphylaxis - etiology</topic><topic>Anesthesia, General</topic><topic>Anesthesiology</topic><topic>Clinical Report</topic><topic>Coronary Vasospasm - etiology</topic><topic>Creatine Kinase - metabolism</topic><topic>Critical Care Medicine</topic><topic>Emergency Medicine</topic><topic>Erythrocyte Transfusion - adverse effects</topic><topic>Humans</topic><topic>Intensive</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Pain Medicine</topic><topic>Transfusion Reaction</topic><topic>Tryptases - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Osugi, Toshihiro</creatorcontrib><creatorcontrib>Ueki, Ryusuke</creatorcontrib><creatorcontrib>Shimode, Noriko</creatorcontrib><creatorcontrib>Tatara, Tsuneo</creatorcontrib><creatorcontrib>Tashiro, Chikara</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Osugi, Toshihiro</au><au>Ueki, Ryusuke</au><au>Shimode, Noriko</au><au>Tatara, Tsuneo</au><au>Tashiro, Chikara</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood transfusion-induced anaphylaxis and coronary artery spasm during general anesthesia</atitle><jtitle>Journal of anesthesia</jtitle><stitle>J Anesth</stitle><addtitle>J Anesth</addtitle><date>2008</date><risdate>2008</risdate><volume>22</volume><issue>4</issue><spage>457</spage><epage>459</epage><pages>457-459</pages><issn>0913-8668</issn><eissn>1438-8359</eissn><abstract>Anaphylactic reactions to blood transfusion can lead to life-threatening cardiovascular disruptions. We describe a case in which anaphylaxis due to blood transfusion during general anesthesia was the probable cause of coronary artery spasm. Thirty minutes after the transfusion of concentrated red blood cells, the patient’s blood pressure had dropped to 70/40 mmHg and peak airway pressure had increased to 35 cmH
2
O. The ST segment of the ECG was simultaneously elevated, and the left upper arm became extensively flushed. The tryptase concentration in the patient’s plasma collected 3 h postoperatively was 13.9 μg·l
−1
(normal range, 2.1–9.0 μg·l
−1
). This case report emphasizes that anaphylactic reactions to blood transfusion can potentially lead to coronary artery spasm.</abstract><cop>Japan</cop><pub>Springer Japan</pub><pmid>19011789</pmid><doi>10.1007/s00540-008-0658-7</doi><tpages>3</tpages></addata></record> |
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subjects | Aged Anaphylaxis - etiology Anesthesia, General Anesthesiology Clinical Report Coronary Vasospasm - etiology Creatine Kinase - metabolism Critical Care Medicine Emergency Medicine Erythrocyte Transfusion - adverse effects Humans Intensive Male Medicine Medicine & Public Health Pain Medicine Transfusion Reaction Tryptases - blood |
title | Blood transfusion-induced anaphylaxis and coronary artery spasm during general anesthesia |
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