[18F]Fluorothymidine Positron Emission Tomography before and 7 Days after Gefitinib Treatment Predicts Response in Patients with Advanced Adenocarcinoma of the Lung

Purpose: To evaluate the usefulness of 3′-deoxy-3′-[ 18 F]fluorothymidine (FLT)-positron emission tomography (PET) for predicting response and patient outcome of gefitinib therapy in patients with adenocarcinoma of the lung. Experimental Design: Nonsmokers with advanced or recurrent adenocarcinoma o...

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Veröffentlicht in:	Clinical cancer research 2008-11, Vol.14 (22), p.7423-7429
Hauptverfasser:	Sohn, Hee-Jung, Yang, You-Jung, Ryu, Jin-Sook, Oh, Seung Jun, Im, Ki Chun, Moon, Dae Hyuk, Lee, Dae Ho, Suh, Cheolwon, Lee, Jung-Shin, Kim, Sang-We
Format:	Artikel
Sprache:	eng
Schlagworte:	adenocarcinoma Adenocarcinoma - diagnostic imaging Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adult Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Female Fluorine Radioisotopes fluorothymidine gefitinib Humans Kaplan-Meier Estimate lung Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Lung Neoplasms - pathology Male Middle Aged Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - pathology Positron-Emission Tomography Prognosis Quinazolines - therapeutic use Radiopharmaceuticals ROC Curve Thymidine Time Tomography, X-Ray Computed
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