Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

Background & Aims: Colon cancer of the microsatellite mutator phenotype (MMP) exhibits significant genotype differences from cancer without the MMP. Twenty-nine MMP-positive gastric cancers were analyzed to clarify if these genotype differences were also associated with distinctive clinicopathol...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1999-06, Vol.116 (6), p.1348-1357
Hauptverfasser:	Yamamoto, Hiroyuki, Perez–Piteira, Javier, Yoshida, Teruhiko, Terada, Masaaki, Itoh, Fumio, Imai, Kohzoh, Perucho, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Base Sequence - genetics beta 2-Microglobulin - genetics Carrier Proteins DNA-Binding Proteins Humans Loss of Heterozygosity Methylation Microsatellite Repeats - genetics Mutation - genetics MutL Protein Homolog 1 MutS Homolog 2 Protein Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Nuclear Proteins Phenotype Promoter Regions, Genetic - physiology Proto-Oncogene Proteins - genetics Stomach Neoplasms - genetics Stomach Neoplasms - pathology Stomach Neoplasms - physiopathology Survival Analysis Tumor Suppressor Protein p53 - genetics
Online-Zugang:	Volltext
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