A Novel Subtype of Prostacyclin Receptor in the Central Nervous System

: Recently, in the course of our search for the prostacyclin receptor in the brain, we found a novel subtype, designated as IP2, which was finely discriminated by use of the specific ligand (15R)‐16‐m‐tolyl‐17,18,19,20‐tetranorisocarbacyclin (15R‐TIC) and specifically localized in the rostral part o...

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Veröffentlicht in:	Journal of neurochemistry 1999-06, Vol.72 (6), p.2583-2592
Hauptverfasser:	Watanabe, Yumiko, Matsumura, Kiyoshi, Takechi, Hajime, Kato, Koichi, Morii, Hiroshi, Björkman, Margareta, Langstrom, Bengt, Noyori, Ryoji, Suzuki, Masaaki, Watanabe, Yasuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Binding, Competitive Biological and medical sciences Brain - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Corpus Striatum - metabolism Epoprostenol - analogs & derivatives Epoprostenol - chemical synthesis Epoprostenol - pharmacokinetics Epoprostenol - pharmacology Fundamental and applied biological sciences. Psychology Kinetics Male Molecular Structure Organ Specificity Prostacyclin receptor prostacyclin receptors Radioligand Assay Rats Rats, Wistar Receptors, Epoprostenol Receptors, Prostaglandin - metabolism Solitary Nucleus - metabolism Thalamus - metabolism Tolyl‐isocarbacyclin Tritium Vertebrates: nervous system and sense organs
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