Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale

Cell-replacement therapy using human embryonic stem cells (hESCs) holds great promise in treating Parkinson's disease. We have recently reported a highly efficient method to generate functional dopaminergic (DA) neurons from hESCs. Our method includes a unique step, the formation of spherical n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature protocols 2008-12, Vol.3 (12), p.1888-1894
Hauptverfasser:	Cho, Myung-Soo, Hwang, Dong-Youn, Kim, Dong-Wook
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Biological Techniques Biomedical and Life Sciences Cell Culture Techniques Cell Differentiation Computational Biology/Bioinformatics Dopamine - metabolism Dopaminergic mechanisms Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - physiology Embryonic Stem Cells - transplantation Flow cytometry Growth factors Humans Life Sciences Methods Microarrays Neurological research Neurons Neurons - cytology Neurons - metabolism Organic Chemistry Parkinson's disease protocol Receptors, Dopamine - metabolism Stem cells
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!