Iodine Balance, Iatrogenic Excess, and Thyroid Dysfunction in Premature Newborns

Iodine is a trace element that is essential for the synthesis of thyroid hormones. The thyroid hormones, thyroxine and 3,5,3′-triiodothyronine, are necessary for adequate growth and development throughout fetal and extrauterine life. The iodine intake of newborns is entirely dependent on the iodine...

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Veröffentlicht in:Seminars in perinatology 2008-12, Vol.32 (6), p.407-412
Hauptverfasser: Ares, Susana, MD, PhD, Quero, Jose, MD, PhD, de Escobar, Gabriella Morreale, PhD
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container_issue 6
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container_title Seminars in perinatology
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creator Ares, Susana, MD, PhD
Quero, Jose, MD, PhD
de Escobar, Gabriella Morreale, PhD
description Iodine is a trace element that is essential for the synthesis of thyroid hormones. The thyroid hormones, thyroxine and 3,5,3′-triiodothyronine, are necessary for adequate growth and development throughout fetal and extrauterine life. The iodine intake of newborns is entirely dependent on the iodine content of breast milk and the formula preparations used to feed them. An inadequate iodine supply (deficiency and excess) might be especially dangerous in the case of premature babies. The minimum recommended dietary allowance is different depending on age groups. The iodine intake required is at least 15 μg/kg/d in full-term infants and 30 μg/kg/d in preterms. Premature infants are in a situation of iodine deficiency, precisely at a stage of psychomotor and neural development that is extremely sensitive to alterations of thyroid function.
doi_str_mv 10.1053/j.semperi.2008.09.006
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects breast milk
Female
Humans
hypothyroidism
Hypothyroidism - blood
Hypothyroidism - metabolism
Infant Formula
Infant, Newborn
Infant, Premature - blood
Infant, Premature - metabolism
Iodine - administration & dosage
Iodine - metabolism
iodine intake
Milk, Human
Neonatal and Perinatal Medicine
Pregnancy
thyroid hormone
Thyroid Hormones - blood
Thyroid Hormones - deficiency
Thyroid Hormones - metabolism
title Iodine Balance, Iatrogenic Excess, and Thyroid Dysfunction in Premature Newborns
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