Latent membrane protein-1 of Epstein-Barr virus induces the expression of B-cell integration cluster, a precursor form of microRNA-155, in B lymphoma cell lines

miR-155, a microRNA, and its precursor form, B-cell integration cluster (BIC), are involved in tumor growth. Epstein-Barr virus (EBV)-associated malignancies are categorized into three types, based on their latent gene expression pattern: latency I, II, and III. In the present study, we found that i...

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Veröffentlicht in:	Biochemical and biophysical research communications 2008-12, Vol.377 (2), p.579-583
Hauptverfasser:	Rahadiani, Nur, Takakuwa, Tetsuya, Tresnasari, Kristianti, Morii, Eiichi, Aozasa, Katsuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - metabolism BIC/miR-155 Cell Line, Tumor EB virus Epstein-Barr virus Herpesvirus 4, Human - metabolism Humans LMP1 Lymphoma Lymphoma, B-Cell - metabolism Lymphoma, B-Cell - virology MicroRNAs - biosynthesis NF-kappa B - metabolism p38 Mitogen-Activated Protein Kinases - metabolism Viral Matrix Proteins - genetics Viral Matrix Proteins - metabolism
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