Cutaneous T-cell lymphoma presenting as benign dermatoses
Cutaneous T-cell lymphoma, also known as mycosis fungoides, is a malignancy of the T helper (CD4+) cells. Diagnosis is difficult early in the course of this disease because it mimics several benign skin disorders, including eczema, psoriasis and contact dermatitis. Cutaneous T-cell lymphoma is also...
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| Veröffentlicht in: | American family physician 1999-05, Vol.59 (10), p.2809-2813 |
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| creator | Elmer, K B George, R M |
| description | Cutaneous T-cell lymphoma, also known as mycosis fungoides, is a malignancy of the T helper (CD4+) cells. Diagnosis is difficult early in the course of this disease because it mimics several benign skin disorders, including eczema, psoriasis and contact dermatitis. Cutaneous T-cell lymphoma is also difficult to identify histologically, and multiple biopsies may be necessary to confirm the diagnosis. Treatment may require a combination of topical and systemic agents. Patients with limited skin disease have a good prognosis, but the prognosis is less hopeful in those with extracutaneous involvement. As the disease progresses, the normal T-cell population is eliminated, and the patient becomes significantly immunosuppressed. Infection is the primary cause of mortality in patients with cutaneous T-cell lymphoma. |
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Diagnosis is difficult early in the course of this disease because it mimics several benign skin disorders, including eczema, psoriasis and contact dermatitis. Cutaneous T-cell lymphoma is also difficult to identify histologically, and multiple biopsies may be necessary to confirm the diagnosis. Treatment may require a combination of topical and systemic agents. Patients with limited skin disease have a good prognosis, but the prognosis is less hopeful in those with extracutaneous involvement. As the disease progresses, the normal T-cell population is eliminated, and the patient becomes significantly immunosuppressed. Infection is the primary cause of mortality in patients with cutaneous T-cell lymphoma.</description><identifier>ISSN: 0002-838X</identifier><identifier>PMID: 10348073</identifier><identifier>CODEN: AFPYBF</identifier><language>eng</language><publisher>United States: American Academy of Family Physicians</publisher><subject>Diagnosis, Differential ; Humans ; Lymphatic Metastasis ; Lymphoma, T-Cell, Cutaneous - complications ; Lymphoma, T-Cell, Cutaneous - diagnosis ; Lymphoma, T-Cell, Cutaneous - pathology ; Medical diagnosis ; Skin cancer ; Skin Diseases - etiology</subject><ispartof>American family physician, 1999-05, Vol.59 (10), p.2809-2813</ispartof><rights>Copyright American Academy of Family Physicians May 15, 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10348073$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elmer, K B</creatorcontrib><creatorcontrib>George, R M</creatorcontrib><title>Cutaneous T-cell lymphoma presenting as benign dermatoses</title><title>American family physician</title><addtitle>Am Fam Physician</addtitle><description>Cutaneous T-cell lymphoma, also known as mycosis fungoides, is a malignancy of the T helper (CD4+) cells. Diagnosis is difficult early in the course of this disease because it mimics several benign skin disorders, including eczema, psoriasis and contact dermatitis. Cutaneous T-cell lymphoma is also difficult to identify histologically, and multiple biopsies may be necessary to confirm the diagnosis. Treatment may require a combination of topical and systemic agents. Patients with limited skin disease have a good prognosis, but the prognosis is less hopeful in those with extracutaneous involvement. As the disease progresses, the normal T-cell population is eliminated, and the patient becomes significantly immunosuppressed. Infection is the primary cause of mortality in patients with cutaneous T-cell lymphoma.</description><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Lymphoma, T-Cell, Cutaneous - complications</subject><subject>Lymphoma, T-Cell, Cutaneous - diagnosis</subject><subject>Lymphoma, T-Cell, Cutaneous - pathology</subject><subject>Medical diagnosis</subject><subject>Skin cancer</subject><subject>Skin Diseases - etiology</subject><issn>0002-838X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkEtLxDAYRbNQnHH0L0hw4a6QV_NYSvEFA25GcFeS5uvYoUlr0i7m31uZcePqcuFwOdwLtCaEsEJz_blC1zkflqpKaq7QihIuNFF8jUw1TzbCMGe8Kxroe9wfw_g1BIvHBBni1MU9thk7iN0-Yg8p2GnIkG_QZWv7DLfn3KCP56dd9Vps31_eqsdtMTIupsIQDSV3LQdNoWzAeU8da6yS3jLDS6EIk0JoYUvmtWwc16b10ipKpRMt8A16OO2OafieIU916PKv6Um7lkZpQShbwPt_4GGYU1zc6sWEU8K0WaC7MzS7AL4eUxdsOtZ_j_AfwaBa7w</recordid><startdate>19990515</startdate><enddate>19990515</enddate><creator>Elmer, K B</creator><creator>George, R M</creator><general>American Academy of Family Physicians</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>19990515</creationdate><title>Cutaneous T-cell lymphoma presenting as benign dermatoses</title><author>Elmer, K B ; George, R M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p234t-908e53bf3e81e5cebdd1b2ca76da2935470264484a52d86cb389fd6a7116b4fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Lymphoma, T-Cell, Cutaneous - complications</topic><topic>Lymphoma, T-Cell, Cutaneous - diagnosis</topic><topic>Lymphoma, T-Cell, Cutaneous - pathology</topic><topic>Medical diagnosis</topic><topic>Skin cancer</topic><topic>Skin Diseases - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elmer, K B</creatorcontrib><creatorcontrib>George, R M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>American family physician</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elmer, K B</au><au>George, R M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cutaneous T-cell lymphoma presenting as benign dermatoses</atitle><jtitle>American family physician</jtitle><addtitle>Am Fam Physician</addtitle><date>1999-05-15</date><risdate>1999</risdate><volume>59</volume><issue>10</issue><spage>2809</spage><epage>2813</epage><pages>2809-2813</pages><issn>0002-838X</issn><coden>AFPYBF</coden><abstract>Cutaneous T-cell lymphoma, also known as mycosis fungoides, is a malignancy of the T helper (CD4+) cells. 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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Diagnosis, Differential Humans Lymphatic Metastasis Lymphoma, T-Cell, Cutaneous - complications Lymphoma, T-Cell, Cutaneous - diagnosis Lymphoma, T-Cell, Cutaneous - pathology Medical diagnosis Skin cancer Skin Diseases - etiology |
| title | Cutaneous T-cell lymphoma presenting as benign dermatoses |
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