Incidence of adverse events related to health care in Spain: results of the Spanish National Study of Adverse Events
Objective: To determine the incidence and incidence density of adverse events (AEs) in Spanish hospitals (including the pre-hospitalisation period). Method: Retrospective cohort study. Results: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and r...
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| Veröffentlicht in: | Journal of epidemiology and community health (1979) 2008-12, Vol.62 (12), p.1022-1029 |
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| container_title | Journal of epidemiology and community health (1979) |
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| creator | Aranaz-Andrés, J M Aibar-Remón, C Vitaller-Murillo, J Ruiz-López, P Limón-Ramírez, R Terol-García, E |
| description | Objective: To determine the incidence and incidence density of adverse events (AEs) in Spanish hospitals (including the pre-hospitalisation period). Method: Retrospective cohort study. Results: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 8.6% to 10.1%), including those from the pre-hospitalisation period. The incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% additional treatments were required. In total 42.8% of AEs were considered as avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs compared with 5.2% of the subjects who had no risk factors (p |
| doi_str_mv | 10.1136/jech.2007.065227 |
| format | Article |
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Method: Retrospective cohort study. Results: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 8.6% to 10.1%), including those from the pre-hospitalisation period. The incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% additional treatments were required. In total 42.8% of AEs were considered as avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs compared with 5.2% of the subjects who had no risk factors (p<0.001), and 9.5% of the subjects who had some extrinsic risk factors developed AEs compared with 3.4% of the subjects who had not (p<0.001). Patients older than 65 years of age showed a higher frequency of AEs than those under this age (12.4% vs 5.4%, p<0.001, RR 2.5). The most frequent AEs were those associated with medication (37.4%), hospital infections of any type (25.3%) and those relating to technical problems during a procedure (25.0%). A total of 31.4% of the AEs involved an increase in the length of stay. The AEs associated with medical assistance caused 6.1 additional hospital stays by patient. Conclusions: The incidence of patients with AE related to medical assistance in Spanish hospitals was relevant and similar to those found in the studies from Canada and New Zealand that had been conducted with comparable methodology. Patient vulnerability has been identified therein as playing a major role in generating healthcare-related AEs. These and other recent results indicate the need for AEs to be considered a public health priority in Europe.</description><identifier>ISSN: 0143-005X</identifier><identifier>EISSN: 1470-2738</identifier><identifier>DOI: 10.1136/jech.2007.065227</identifier><identifier>PMID: 19008366</identifier><identifier>CODEN: JECHDR</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Age Factors ; Aged ; Biological and medical sciences ; Bombings ; Clinical medicine ; Cohort Studies ; Community health ; Delivery of Health Care - statistics & numerical data ; General aspects ; Health care ; Health Facility Size ; Hospital admissions ; Hospitalization ; Hospitalization - statistics & numerical data ; Hospitals ; Humans ; Iatrogenic Disease - epidemiology ; Incidence ; Length of Stay ; Medical Audit ; Medical Errors - statistics & numerical data ; Medical practice ; Medical records ; Medical sciences ; Medications ; Middle Aged ; Miscellaneous ; Objectives ; Patients ; Predisposing factors ; Public health ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Quality ; Research reports ; Retrospective Studies ; Risk Factors ; Sample size ; Spain - epidemiology ; Studies ; Surgical procedures ; Teaching hospitals</subject><ispartof>Journal of epidemiology and community health (1979), 2008-12, Vol.62 (12), p.1022-1029</ispartof><rights>2008 the BMJ Publishing Group</rights><rights>Copyright © 2008 BMJ Publishing Group</rights><rights>2009 INIST-CNRS</rights><rights>Copyright: 2008 2008 the BMJ Publishing Group</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b451t-ca586a9c82b5bc7e5decb5fb077934d0e3dccd65a17343561f2ea57d54a30b8f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jech.bmj.com/content/62/12/1022.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttps://jech.bmj.com/content/62/12/1022.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,799,3183,23550,27901,27902,57992,58225,77343,77374</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20833233$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19008366$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aranaz-Andrés, J M</creatorcontrib><creatorcontrib>Aibar-Remón, C</creatorcontrib><creatorcontrib>Vitaller-Murillo, J</creatorcontrib><creatorcontrib>Ruiz-López, P</creatorcontrib><creatorcontrib>Limón-Ramírez, R</creatorcontrib><creatorcontrib>Terol-García, E</creatorcontrib><creatorcontrib>ENEAS work group</creatorcontrib><creatorcontrib>ENEAS work group</creatorcontrib><creatorcontrib>the ENEAS work group</creatorcontrib><title>Incidence of adverse events related to health care in Spain: results of the Spanish National Study of Adverse Events</title><title>Journal of epidemiology and community health (1979)</title><addtitle>J Epidemiol Community Health</addtitle><description>Objective: To determine the incidence and incidence density of adverse events (AEs) in Spanish hospitals (including the pre-hospitalisation period). Method: Retrospective cohort study. Results: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 8.6% to 10.1%), including those from the pre-hospitalisation period. The incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% additional treatments were required. In total 42.8% of AEs were considered as avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs compared with 5.2% of the subjects who had no risk factors (p<0.001), and 9.5% of the subjects who had some extrinsic risk factors developed AEs compared with 3.4% of the subjects who had not (p<0.001). Patients older than 65 years of age showed a higher frequency of AEs than those under this age (12.4% vs 5.4%, p<0.001, RR 2.5). The most frequent AEs were those associated with medication (37.4%), hospital infections of any type (25.3%) and those relating to technical problems during a procedure (25.0%). A total of 31.4% of the AEs involved an increase in the length of stay. The AEs associated with medical assistance caused 6.1 additional hospital stays by patient. Conclusions: The incidence of patients with AE related to medical assistance in Spanish hospitals was relevant and similar to those found in the studies from Canada and New Zealand that had been conducted with comparable methodology. Patient vulnerability has been identified therein as playing a major role in generating healthcare-related AEs. These and other recent results indicate the need for AEs to be considered a public health priority in Europe.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Bombings</subject><subject>Clinical medicine</subject><subject>Cohort Studies</subject><subject>Community health</subject><subject>Delivery of Health Care - statistics & numerical data</subject><subject>General aspects</subject><subject>Health care</subject><subject>Health Facility Size</subject><subject>Hospital admissions</subject><subject>Hospitalization</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Iatrogenic Disease - epidemiology</subject><subject>Incidence</subject><subject>Length of Stay</subject><subject>Medical Audit</subject><subject>Medical Errors - statistics & numerical data</subject><subject>Medical practice</subject><subject>Medical records</subject><subject>Medical sciences</subject><subject>Medications</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Objectives</subject><subject>Patients</subject><subject>Predisposing factors</subject><subject>Public health</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Quality</subject><subject>Research reports</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sample size</subject><subject>Spain - epidemiology</subject><subject>Studies</subject><subject>Surgical procedures</subject><subject>Teaching hospitals</subject><issn>0143-005X</issn><issn>1470-2738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc1v1DAUxC0EokvhzgVkCcGlyuKP2E64VasClVbl0FIQF8uxX5Qs2WRrOxX97-uQqCAu-GLL83vzNBqEXlKyppTL9zuwzZoRotZECsbUI7SiuSIZU7x4jFaE5jwjRHw_Qs9C2JH0VKx8io5oSUjBpVyheN7b1kFvAQ81Nu4WfAAMt9DHgD10JoLDccANmC422BoPuO3x5cG0_YcEhLFLYBqNDUy_fRsafGFiO_Smw5dxdHeTeroYn_02fo6e1KYL8GK5j9HXj2dXm8_Z9sun883pNqtyQWNmjSikKW3BKlFZBcKBrURdEaVKnjsC3FnrpDBU8ZwLSWsGRigncsNJVdT8GL2bfQ9-uBkhRL1vg4WuMz0MY9CyVAVLJ4Fv_gF3w-hTgqBpWsYkUYImisyU9UMIHmp98O3e-DtNiZ760FMfeupDz32kkdeL8Vjtwf0ZWApIwNsFMMGarvYm9REeOJYozjhP3KuZ24U4-L90lRA1-WSz3oYIvx50439qqbgS-uJ6o8vrqx_827bQU5aTma_2u__HuAdbIbnt</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>Aranaz-Andrés, J M</creator><creator>Aibar-Remón, C</creator><creator>Vitaller-Murillo, J</creator><creator>Ruiz-López, P</creator><creator>Limón-Ramírez, R</creator><creator>Terol-García, E</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20081201</creationdate><title>Incidence of adverse events related to health care in Spain: results of the Spanish National Study of Adverse Events</title><author>Aranaz-Andrés, J M ; Aibar-Remón, C ; Vitaller-Murillo, J ; Ruiz-López, P ; Limón-Ramírez, R ; Terol-García, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b451t-ca586a9c82b5bc7e5decb5fb077934d0e3dccd65a17343561f2ea57d54a30b8f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Bombings</topic><topic>Clinical medicine</topic><topic>Cohort Studies</topic><topic>Community health</topic><topic>Delivery of Health Care - statistics & numerical data</topic><topic>General aspects</topic><topic>Health care</topic><topic>Health Facility Size</topic><topic>Hospital admissions</topic><topic>Hospitalization</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Iatrogenic Disease - epidemiology</topic><topic>Incidence</topic><topic>Length of Stay</topic><topic>Medical Audit</topic><topic>Medical Errors - statistics & numerical data</topic><topic>Medical practice</topic><topic>Medical records</topic><topic>Medical sciences</topic><topic>Medications</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Objectives</topic><topic>Patients</topic><topic>Predisposing factors</topic><topic>Public health</topic><topic>Public health. 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Method: Retrospective cohort study. Results: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 8.6% to 10.1%), including those from the pre-hospitalisation period. The incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% additional treatments were required. In total 42.8% of AEs were considered as avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs compared with 5.2% of the subjects who had no risk factors (p<0.001), and 9.5% of the subjects who had some extrinsic risk factors developed AEs compared with 3.4% of the subjects who had not (p<0.001). Patients older than 65 years of age showed a higher frequency of AEs than those under this age (12.4% vs 5.4%, p<0.001, RR 2.5). The most frequent AEs were those associated with medication (37.4%), hospital infections of any type (25.3%) and those relating to technical problems during a procedure (25.0%). A total of 31.4% of the AEs involved an increase in the length of stay. The AEs associated with medical assistance caused 6.1 additional hospital stays by patient. Conclusions: The incidence of patients with AE related to medical assistance in Spanish hospitals was relevant and similar to those found in the studies from Canada and New Zealand that had been conducted with comparable methodology. Patient vulnerability has been identified therein as playing a major role in generating healthcare-related AEs. These and other recent results indicate the need for AEs to be considered a public health priority in Europe.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>19008366</pmid><doi>10.1136/jech.2007.065227</doi><tpages>8</tpages></addata></record> |
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| ispartof | Journal of epidemiology and community health (1979), 2008-12, Vol.62 (12), p.1022-1029 |
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| source | Jstor Complete Legacy; MEDLINE; BMJ Journals - NESLi2 |
| subjects | Age Factors Aged Biological and medical sciences Bombings Clinical medicine Cohort Studies Community health Delivery of Health Care - statistics & numerical data General aspects Health care Health Facility Size Hospital admissions Hospitalization Hospitalization - statistics & numerical data Hospitals Humans Iatrogenic Disease - epidemiology Incidence Length of Stay Medical Audit Medical Errors - statistics & numerical data Medical practice Medical records Medical sciences Medications Middle Aged Miscellaneous Objectives Patients Predisposing factors Public health Public health. Hygiene Public health. Hygiene-occupational medicine Quality Research reports Retrospective Studies Risk Factors Sample size Spain - epidemiology Studies Surgical procedures Teaching hospitals |
| title | Incidence of adverse events related to health care in Spain: results of the Spanish National Study of Adverse Events |
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