BARBITURATE INFUSION FOR INTRACTABLE INTRACRANIAL HYPERTENSION AND ITS EFFECT ON BRAIN OXYGENATION

Abstract OBJECTIVE Barbiturate-induced coma can be used in patients to treat intractable intracranial hypertension when other therapies, such as osmotic therapy and sedation, have failed. Despite control of intracranial pressure, cerebral infarction may still occur in some patients, and the effect o...

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Veröffentlicht in:	Neurosurgery 2008-11, Vol.63 (5), p.880-887
Hauptverfasser:	Chen, H. Isaac, Malhotra, Neil R., Oddo, Mauro, Heuer, Gregory G., Levine, Joshua M., LeRoux, Peter D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Barbiturates - administration & dosage Brain - blood supply Brain - drug effects Brain - metabolism Brain Injuries - complications Brain Injuries - physiopathology Critical Care - methods Dose-Response Relationship, Drug Drugs Female Humans Hypertension Infusions, Intravenous Intracranial Hypertension - drug therapy Intracranial Hypertension - etiology Intracranial Hypertension - physiopathology Intracranial Pressure - drug effects Male Middle Aged Monitoring, Physiologic Oxygen - metabolism Retrospective Studies Treatment Outcome
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