Exaggerated endothelin release in high-altitude pulmonary edema

Exaggerated pulmonary hypertension is thought to play an important part in the pathogenesis of high-altitude pulmonary edema (HAPE). Endothelin-1 is a potent pulmonary vasoconstrictor peptide that also augments microvascular permeability. We measured endothelin-1 plasma levels and pulmonary artery p...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1999-05, Vol.99 (20), p.2665-2668
Hauptverfasser:	SARTORI, C, VOLLENWEIDER, L, LÖFFLER, B.-M, DELABAYS, A, NICOD, P, BÄRTSCH, P, SCHERRER, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Altitude Biological and medical sciences Blood Pressure - physiology Disease Susceptibility Endothelin-1 - blood Endothelin-1 - metabolism Female Humans Male Medical sciences Middle Aged Mountaineering - physiology Pneumology Pulmonary Artery - physiopathology Pulmonary Edema - etiology Pulmonary Edema - metabolism Pulmonary Edema - physiopathology Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Systole
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