Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations

Patients experiencing massive haemorrhage are at high risk of developing coagulopathy through loss, consumption, and dilution of coagulation factors and platelets. It has been reported that plasma fibrinogen concentrations may reach a critical low level relatively early during bleeding, calling for...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2008-12, Vol.101 (6), p.769-773
Hauptverfasser:	Fenger-Eriksen, C., Lindberg-Larsen, M., Christensen, A.Q., Ingerslev, J., Sørensen, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Afibrinogenemia - blood Afibrinogenemia - drug therapy Afibrinogenemia - etiology Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences blood Blood Component Transfusion Blood Loss, Surgical - prevention & control blood, coagulation blood, transfusion Child Child, Preschool coagulation coagulopathy complications complications, coagulopathy drug drug delivery Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Fibrinogen - metabolism Fibrinogen - therapeutic use Hemorrhage - blood Hemorrhage - complications Hemorrhage - drug therapy Hemostasis, Surgical - methods Humans Infant Intensive care medicine Male Medical sciences Middle Aged Platelet Count Retrospective Studies safety safety, drug transfusion Treatment Outcome Young Adult
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