Biopositive Effects of Low-Dose UVB on Epidermis: Coordinate Upregulation of Antimicrobial Peptides and Permeability Barrier Reinforcement

Whereas high-dose ultraviolet B (UVB) is detrimental to the epidermal permeability barrier, suberythemal doses of UVB are used to treat atopic dermatitis (AD), which is characterized by defective permeability barrier and antimicrobial function. As epidermal permeability barrier and antimicrobial pep...

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Veröffentlicht in:	Journal of investigative dermatology 2008-12, Vol.128 (12), p.2880-2887
Hauptverfasser:	Hong, Seung P., Kim, Min J., Jung, Min-young, Jeon, Hyerin, Goo, Jawoong, Ahn, Sung K., Lee, Seung H., Elias, Peter M., Choi, Eung H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Cationic Peptides - pharmacology Biological and medical sciences Cathelicidins Cell Differentiation Cholecalciferol - metabolism Dermatology Epidermis - immunology Epidermis - radiation effects Female Immunohistochemistry Ketoconazole - pharmacology Lipids - chemistry Medical sciences Mice Mice, Hairless Models, Biological Permeability Receptors, Calcitriol - metabolism Ultraviolet Rays
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