Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation

The Salmonella typhimurium type III secretion effector protein SifA is essential for inducing tubulation of the Salmonella phagosome and binds the mammalian kinesin-binding protein SKIP. Coexpression of SifA with the effector SseJ induced tubulation of mammalian cell endosomes, similar to that induc...

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Veröffentlicht in:Cell host & microbe 2008-11, Vol.4 (5), p.434-446
Hauptverfasser: Ohlson, Maikke B, Huang, Zhiwei, Alto, Neal M, Blanc, Marie-Pierre, Dixon, Jack E, Chai, Jijie, Miller, Samuel I
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Sprache:eng
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