Parathyroid hormone-related peptide (PTHrP) induces parietal endoderm formation exclusively via the Type I PTH/PTHrP receptor

A number of studies suggest a role for PTHrP and the classical PTH/PTHrP receptor (type I) in one of the first differentiation processes in mouse embryogenesis, i.e. the formation of parietal endoderm (PE). We previously reported that although in type I receptor (−/−) embryos PE formation seemed nor...

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Veröffentlicht in:	Mechanisms of development 1999-03, Vol.81 (1), p.151-161
Hauptverfasser:	Verheijen, Mark H.G, Karperien, Marcel, Chung, Ung-il, van Wijuen, Merel, Heystek, Heleen, Hendriks, Jeanine A.A, Veltmaat, Jacqueline M, Lanske, Beate, Li, En, Löwik, Clemens W.G.M, de Laat, Siegfried W, Kronenberg, Henry M, Defize, Libert H.K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cells, Cultured COS Cells Ectoderm - physiology Embryo, Mammalian - metabolism Embryo, Mammalian - pathology Embryonal stem cells Female Fluorescent Antibody Technique Gene Expression Regulation, Developmental Homologous recombination Immunohistochemistry Male Mice Mice, Inbred C57BL Mice, Inbred CBA Parathyroid hormone-related peptide Parathyroid Hormone-Related Protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parietal endoderm Proteins - analysis Proteins - physiology Receptor, Parathyroid Hormone, Type 1 Receptors, Parathyroid Hormone - analysis Receptors, Parathyroid Hormone - physiology Stem Cells - metabolism Thrombomodulin - metabolism Time Factors Transfection
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