Influence of Chronic Exercise on the Amphetamine-Induced Dopamine Release and Neurodegeneration in the Striatum of the Rat

The aim of this study was to verify the effect of chronic exercise on the striatal dopamine (DA) outflow induced by low and high single doses of amphetamine (AMPH), and verify the existence of an exercise protective role on neurodegeneration. Adult male Sprague‐Dawley rats were randomly separated in...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2008-10, Vol.1139 (1), p.222-231
Hauptverfasser:	Marques, Elsa, Vasconcelos, Filipa, Rolo, Marta R., Pereira, Frederico C., Silva, Ana P., Macedo, Tice R., Ribeiro, Carlos F.
Format:	Artikel
Sprache:	eng
Schlagworte:	amphetamine Amphetamine - pharmacology Animals Central Nervous System Stimulants - pharmacology chronic exercise Corpus Striatum - drug effects Corpus Striatum - metabolism dopamine Dopamine - metabolism Fluoro-Jade C Humans Male Microdialysis Nerve Degeneration - chemically induced neurodegeneration Physical Conditioning, Animal - physiology Random Allocation Rats Rats, Sprague-Dawley striatum
Online-Zugang:	Volltext
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