On the edge: the physiological and pathophysiological role of chemokines during inflammatory and immunological responses

Most, if not all, chemokines bind to seven transmembrane spanning G protein-coupled receptors and activate cellular migration. Stimulated chemokine expression is essential for directing leukocyte emigration from the circulation into sites of inflammation and tissue damage. In contrast, constitutive...

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Veröffentlicht in:Seminars in immunology 1999-04, Vol.11 (2), p.95-104
Hauptverfasser: DeVries, Mark E., Ran, L., Kelvin, David J.
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Sprache:eng
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