Chemical modifications and structure activity studies of ziracin and related everninomicin antibiotics

Chemical modifications of everninomicin antibiotics, particularly ziracin ( 1), were carried out to study the SARs as well as the chemical properties of this class of compounds. Use of allyl ether group for protection and selective deprotection of phenolic groups provided access to a variety of nove...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 1999-04, Vol.9 (8), p.1209-1214
Hauptverfasser:	Ganguly, Ashit K, McCormick, Jinping L, Saksena, Anil K, Das, Pradip R, Chan, Tze-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Enterococcus - drug effects Medical sciences Pharmacology. Drug treatments Staphylococcus - drug effects Structure-Activity Relationship
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