Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function

Live probiotic bacteria are effective in reducing gut permeability and inflammation. We have previously shown that probiotics release peptide bioactive factors that modulate epithelial resistance in vitro. The objectives of this study were to determine the impact of factors released from Bifidobacte...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2008-11, Vol.295 (5), p.G1025-G1034
Hauptverfasser:	Ewaschuk, Julia B, Diaz, Hugo, Meddings, Liisa, Diederichs, Brendan, Dmytrash, Andrea, Backer, Jody, Looijer-van Langen, Mirjam, Madsen, Karen L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Bacteria Bifidobacterium - chemistry Bifidobacterium - metabolism Cell Line, Tumor Cells Culture Media, Conditioned - chemistry Culture Media, Conditioned - pharmacology Cytokines Gene Deletion Gene Expression Regulation Humans Interleukin-10 - genetics Interleukin-10 - metabolism Intestines - drug effects Intestines - microbiology Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mitogen-Activated Protein Kinase Kinases - metabolism Peptides Permeability Phosphorylation Probiotics Rodents
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