A PDZ Protein Regulates the Distribution of the Transmembrane Semaphorin, M-SemF

M-SemF is a membrane-associated, neurally enriched member of the semaphorin family of axon guidance signals. We considered whether the cytoplasmic domain of M-SemF might possess a signaling function and/or might control the distribution of M-SemF on the cell surface. We identify a PDZ-containing neu...

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Veröffentlicht in:	The Journal of biological chemistry 1999-05, Vol.274 (20), p.14137-14146
Hauptverfasser:	Wang, Li-Hsien, Kalb, Robert G., Strittmatter, Stephen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Amino Acid Sequence Animals Brain - metabolism Carrier Proteins - metabolism Cell Line Fluorescent Antibody Technique, Indirect Humans Lung - metabolism M-SemF protein Membrane Proteins - metabolism Mice Molecular Sequence Data Nerve Growth Factors - metabolism Neuropeptides - metabolism PDZ protein Phosphoproteins - metabolism Rabbits RGS Proteins Semaphorins Signal Transduction
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