Association of Major Depressive Disorder With Altered Functional Brain Response During Anticipation and Processing of Heat Pain

CONTEXT Chronic pain and depression are highly comorbid conditions, yet little is known about the neurobiological basis of pain processing in major depressive disorder (MDD). OBJECTIVE To examine the neural substrates underlying anticipation and processing of heat pain in a group of unmedicated youn...

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Veröffentlicht in:	Archives of general psychiatry 2008-11, Vol.65 (11), p.1275-1284
Hauptverfasser:	Strigo, Irina A, Simmons, Alan N, Matthews, Scott C, Craig, Arthur D. (Bud), Paulus, Martin P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adult and adolescent clinical studies Affect - physiology Amygdala - physiopathology Arousal - physiology Attention - physiology Biological and medical sciences Brain - physiopathology Brain Mapping Cerebral Cortex - physiology Color Perception - physiology Culture Depression Depressive Disorder, Major - diagnosis Depressive Disorder, Major - physiopathology Depressive Disorder, Major - psychology Female Gyrus Cinguli - physiopathology Helplessness, Learned Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medical sciences Mood disorders Oxygen - blood Pain - physiopathology Pain Measurement Pain Threshold - physiology Periaqueductal Gray - physiopathology Prefrontal Cortex - physiology Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - physiology Psychopathology. Psychiatry Set (Psychology) Thermosensing - physiology
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