MPC‐1−CD49e− immature myeloma cells include CD45+ subpopulations that can proliferate in response to IL‐6 in human myelomas

Using three‐colour phenotypic analysis, we detected five subpopulations of myeloma cells (CD38++) in the bone marrow mononuclear cells of human myeloma patients: MPC‐1−CD45−CD49e−, MPC‐1−CD45+CD49e−, MPC‐1+CD45−CD49e−, MPC‐1+CD45+CD49e− and MPC‐1+CD45+CD49e+. Most of the myeloma cells did not expres...

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