Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report

ABSTRACT OBJECTIVE Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history o...

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Veröffentlicht in:Neurosurgery 2008-10, Vol.63 (4), p.E813-E814
Hauptverfasser: Ayberk, Giyas, Ozveren, Mehmet F., Uzum, Nuket, Tosun, Ozgur, Akcay, Emine K.
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container_end_page E814
container_issue 4
container_start_page E813
container_title Neurosurgery
container_volume 63
creator Ayberk, Giyas
Ozveren, Mehmet F.
Uzum, Nuket
Tosun, Ozgur
Akcay, Emine K.
description ABSTRACT OBJECTIVE Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS. CONCLUSION The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.
doi_str_mv 10.1227/01.NEU.0000325501.75772.FD
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This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS. CONCLUSION The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</description><identifier>ISSN: 0148-396X</identifier><identifier>EISSN: 1524-4040</identifier><identifier>DOI: 10.1227/01.NEU.0000325501.75772.FD</identifier><identifier>PMID: 18981849</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Abducens Nerve Diseases - etiology ; Adolescent ; Case reports ; Cornea ; Facial Nerve - pathology ; Facial Nerve - surgery ; Facial Nerve Diseases - etiology ; Female ; Humans ; Magnetic Resonance Imaging ; Neurilemmoma - complications ; Neurilemmoma - diagnosis ; Neurilemmoma - surgery ; Neurological disorders ; Neurosurgical Procedures - methods ; Rare Diseases ; Recovery of Function ; Tomography, X-Ray Computed ; Xerophthalmia - etiology</subject><ispartof>Neurosurgery, 2008-10, Vol.63 (4), p.E813-E814</ispartof><rights>2008 by the Congress of Neurological Surgeons</rights><rights>Copyright © Congress of Neurological Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c249t-59b77800f0878d8547de9645bc00648c12cf33b7d194cfd6fc274728ce83711f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18981849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ayberk, Giyas</creatorcontrib><creatorcontrib>Ozveren, Mehmet F.</creatorcontrib><creatorcontrib>Uzum, Nuket</creatorcontrib><creatorcontrib>Tosun, Ozgur</creatorcontrib><creatorcontrib>Akcay, Emine K.</creatorcontrib><title>Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report</title><title>Neurosurgery</title><addtitle>Neurosurgery</addtitle><description>ABSTRACT OBJECTIVE Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS. CONCLUSION The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</description><subject>Abducens Nerve Diseases - etiology</subject><subject>Adolescent</subject><subject>Case reports</subject><subject>Cornea</subject><subject>Facial Nerve - pathology</subject><subject>Facial Nerve - surgery</subject><subject>Facial Nerve Diseases - etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Neurilemmoma - complications</subject><subject>Neurilemmoma - diagnosis</subject><subject>Neurilemmoma - surgery</subject><subject>Neurological disorders</subject><subject>Neurosurgical Procedures - methods</subject><subject>Rare Diseases</subject><subject>Recovery of Function</subject><subject>Tomography, X-Ray Computed</subject><subject>Xerophthalmia - etiology</subject><issn>0148-396X</issn><issn>1524-4040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqVkVFv1SAUgIlxcdfpXzBEE996BxQK7G25250my1zUJXsjlJ7aLm2pQF326D8Xvdcs2dt4AXK-cziHD6H3lKwpY_KY0PXV-c2a5FUyIfJVCinZenv2Aq2oYLzghJOXaEUoV0Wpq9tD9DrGO0JoxaV6hQ6p0ooqrlfo9waGYRlswN9cd2-nyY8W-xanDvBFAJsgR5YZQtu73g74GlLwMR-uIPwCfB0gwpT66Qe-71OHT-tmcTDF_2E7xAdspwbfQvBzlzo7jL09wRsbAX-F2Yf0Bh20GYO3-_0I3WzPv28-FZdfLj5vTi8Lx7hOhdC1lIqQliipGiW4bEBXXNSOkIorR5lry7KWDdXctU3VOia5ZMqBKiWlbXmEPu7qzsH_XCAmM_bR5entBH6JptKSl7LSGfzwBLzzS5hyb4ZqJSrNNKOZOtlRLv9HDNCaOfSjDQ-GEvNXkyHUZE3mUZP5p8lsz3Lyu_0TSz1C85i695IBsQP8Mj-n8B81lJ6T</recordid><startdate>200810</startdate><enddate>200810</enddate><creator>Ayberk, Giyas</creator><creator>Ozveren, Mehmet F.</creator><creator>Uzum, Nuket</creator><creator>Tosun, Ozgur</creator><creator>Akcay, Emine K.</creator><general>Oxford University Press</general><general>Wolters Kluwer Health, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200810</creationdate><title>Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report</title><author>Ayberk, Giyas ; 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This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS. CONCLUSION The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>18981849</pmid><doi>10.1227/01.NEU.0000325501.75772.FD</doi></addata></record>
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subjects Abducens Nerve Diseases - etiology
Adolescent
Case reports
Cornea
Facial Nerve - pathology
Facial Nerve - surgery
Facial Nerve Diseases - etiology
Female
Humans
Magnetic Resonance Imaging
Neurilemmoma - complications
Neurilemmoma - diagnosis
Neurilemmoma - surgery
Neurological disorders
Neurosurgical Procedures - methods
Rare Diseases
Recovery of Function
Tomography, X-Ray Computed
Xerophthalmia - etiology
title Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report
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