Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report
ABSTRACT OBJECTIVE Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia. CLINICAL PRESENTATION A 16-year-old female patient presented with a 1-month history o...
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Veröffentlicht in: | Neurosurgery 2008-10, Vol.63 (4), p.E813-E814 |
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creator | Ayberk, Giyas Ozveren, Mehmet F. Uzum, Nuket Tosun, Ozgur Akcay, Emine K. |
description | ABSTRACT
OBJECTIVE
Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia.
CLINICAL PRESENTATION
A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS.
CONCLUSION
The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass. |
doi_str_mv | 10.1227/01.NEU.0000325501.75772.FD |
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OBJECTIVE
Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia.
CLINICAL PRESENTATION
A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS.
CONCLUSION
The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</description><identifier>ISSN: 0148-396X</identifier><identifier>EISSN: 1524-4040</identifier><identifier>DOI: 10.1227/01.NEU.0000325501.75772.FD</identifier><identifier>PMID: 18981849</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Abducens Nerve Diseases - etiology ; Adolescent ; Case reports ; Cornea ; Facial Nerve - pathology ; Facial Nerve - surgery ; Facial Nerve Diseases - etiology ; Female ; Humans ; Magnetic Resonance Imaging ; Neurilemmoma - complications ; Neurilemmoma - diagnosis ; Neurilemmoma - surgery ; Neurological disorders ; Neurosurgical Procedures - methods ; Rare Diseases ; Recovery of Function ; Tomography, X-Ray Computed ; Xerophthalmia - etiology</subject><ispartof>Neurosurgery, 2008-10, Vol.63 (4), p.E813-E814</ispartof><rights>2008 by the Congress of Neurological Surgeons</rights><rights>Copyright © Congress of Neurological Surgeons</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c249t-59b77800f0878d8547de9645bc00648c12cf33b7d194cfd6fc274728ce83711f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18981849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ayberk, Giyas</creatorcontrib><creatorcontrib>Ozveren, Mehmet F.</creatorcontrib><creatorcontrib>Uzum, Nuket</creatorcontrib><creatorcontrib>Tosun, Ozgur</creatorcontrib><creatorcontrib>Akcay, Emine K.</creatorcontrib><title>Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report</title><title>Neurosurgery</title><addtitle>Neurosurgery</addtitle><description>ABSTRACT
OBJECTIVE
Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia.
CLINICAL PRESENTATION
A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS.
CONCLUSION
The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</description><subject>Abducens Nerve Diseases - etiology</subject><subject>Adolescent</subject><subject>Case reports</subject><subject>Cornea</subject><subject>Facial Nerve - pathology</subject><subject>Facial Nerve - surgery</subject><subject>Facial Nerve Diseases - etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Neurilemmoma - complications</subject><subject>Neurilemmoma - diagnosis</subject><subject>Neurilemmoma - surgery</subject><subject>Neurological disorders</subject><subject>Neurosurgical Procedures - methods</subject><subject>Rare Diseases</subject><subject>Recovery of Function</subject><subject>Tomography, X-Ray Computed</subject><subject>Xerophthalmia - etiology</subject><issn>0148-396X</issn><issn>1524-4040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqVkVFv1SAUgIlxcdfpXzBEE996BxQK7G25250my1zUJXsjlJ7aLm2pQF326D8Xvdcs2dt4AXK-cziHD6H3lKwpY_KY0PXV-c2a5FUyIfJVCinZenv2Aq2oYLzghJOXaEUoV0Wpq9tD9DrGO0JoxaV6hQ6p0ooqrlfo9waGYRlswN9cd2-nyY8W-xanDvBFAJsgR5YZQtu73g74GlLwMR-uIPwCfB0gwpT66Qe-71OHT-tmcTDF_2E7xAdspwbfQvBzlzo7jL09wRsbAX-F2Yf0Bh20GYO3-_0I3WzPv28-FZdfLj5vTi8Lx7hOhdC1lIqQliipGiW4bEBXXNSOkIorR5lry7KWDdXctU3VOia5ZMqBKiWlbXmEPu7qzsH_XCAmM_bR5entBH6JptKSl7LSGfzwBLzzS5hyb4ZqJSrNNKOZOtlRLv9HDNCaOfSjDQ-GEvNXkyHUZE3mUZP5p8lsz3Lyu_0TSz1C85i695IBsQP8Mj-n8B81lJ6T</recordid><startdate>200810</startdate><enddate>200810</enddate><creator>Ayberk, Giyas</creator><creator>Ozveren, Mehmet F.</creator><creator>Uzum, Nuket</creator><creator>Tosun, Ozgur</creator><creator>Akcay, Emine K.</creator><general>Oxford University Press</general><general>Wolters Kluwer Health, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200810</creationdate><title>Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report</title><author>Ayberk, Giyas ; Ozveren, Mehmet F. ; Uzum, Nuket ; Tosun, Ozgur ; Akcay, Emine K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c249t-59b77800f0878d8547de9645bc00648c12cf33b7d194cfd6fc274728ce83711f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Abducens Nerve Diseases - etiology</topic><topic>Adolescent</topic><topic>Case reports</topic><topic>Cornea</topic><topic>Facial Nerve - pathology</topic><topic>Facial Nerve - surgery</topic><topic>Facial Nerve Diseases - etiology</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Neurilemmoma - complications</topic><topic>Neurilemmoma - diagnosis</topic><topic>Neurilemmoma - surgery</topic><topic>Neurological disorders</topic><topic>Neurosurgical Procedures - methods</topic><topic>Rare Diseases</topic><topic>Recovery of Function</topic><topic>Tomography, X-Ray Computed</topic><topic>Xerophthalmia - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ayberk, Giyas</creatorcontrib><creatorcontrib>Ozveren, Mehmet F.</creatorcontrib><creatorcontrib>Uzum, Nuket</creatorcontrib><creatorcontrib>Tosun, Ozgur</creatorcontrib><creatorcontrib>Akcay, Emine K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ayberk, Giyas</au><au>Ozveren, Mehmet F.</au><au>Uzum, Nuket</au><au>Tosun, Ozgur</au><au>Akcay, Emine K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report</atitle><jtitle>Neurosurgery</jtitle><addtitle>Neurosurgery</addtitle><date>2008-10</date><risdate>2008</risdate><volume>63</volume><issue>4</issue><spage>E813</spage><epage>E814</epage><pages>E813-E814</pages><issn>0148-396X</issn><eissn>1524-4040</eissn><abstract>ABSTRACT
OBJECTIVE
Cellular schwannomas (CS) are rare in the cranial space. This report is the first of a patient with a greater superficial petrosal nerve CS presenting with abducens nerve palsy and xerophthalmia.
CLINICAL PRESENTATION
A 16-year-old female patient presented with a 1-month history of diplopia. Neurological examination was normal except for the presence of right abducens nerve palsy. Schirmer's test revealed decreased tear secretion in the right eye. Computed tomography and magnetic resonance imaging showed a mass in the right petrous apex. It was thought that the schwannoma in our patient originated from the greater superficial petrosal nerve, based on the location of the tumor in addition to the absence of partial Horner's syndrome and a persistent decrease in tear secretion. INTERVENTION: The tumor was exposed with the use of a right subtemporal extradural approach and removed entirely. Pathological evaluation of the tumor revealed a CS.
CONCLUSION
The abducens nerve palsy improved completely in the follow-up period, but the decreased tear secretion did not resolve. CS is one of the subtypes of ordinary schwannomas and exhibits malignant features on microscopic examination, although it has a good clinical prognosis. No adjuvant treatment was applied because of the tumor's benign character. The greater superficial petrosal nerve schwannoma should be considered in the differential diagnosis of the abducens nerve palsy and petrous apex mass.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>18981849</pmid><doi>10.1227/01.NEU.0000325501.75772.FD</doi></addata></record> |
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source | MEDLINE; Journals@Ovid Complete |
subjects | Abducens Nerve Diseases - etiology Adolescent Case reports Cornea Facial Nerve - pathology Facial Nerve - surgery Facial Nerve Diseases - etiology Female Humans Magnetic Resonance Imaging Neurilemmoma - complications Neurilemmoma - diagnosis Neurilemmoma - surgery Neurological disorders Neurosurgical Procedures - methods Rare Diseases Recovery of Function Tomography, X-Ray Computed Xerophthalmia - etiology |
title | Cellular Schwannoma of the Greater Superficial Petrosal Nerve Presenting with Abducens Nerve Palsy and Xerophthalmia: Case Report |
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