Conformational analyses of cyclic hexapeptide analogs of somatostatin containing arylalkyl peptoid and naphthylalanine residues

We report the conformational analysis by 1H‐NMR in DMSO and computer simulations involving distance geometry and molecular dynamics simulations of peptoid analogs of the cyclic hexapeptide c‐[Phe11‐Pro6‐Phe7‐d‐Trp8‐Lys9‐Thr10] L‐363,301 (the numbering refers to the positions in native somatostatin)....

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Veröffentlicht in:	Journal of peptide science 1999-04, Vol.5 (4), p.161-175
Hauptverfasser:	Mattern, Ralph-Heiko, Tran, Thuy-Anh, Goodman, Murray
Format:	Artikel
Sprache:	eng
Schlagworte:	1H-NMR Alanine - analogs & derivatives Alanine - chemistry Computer Simulation computer simulations conformational analysis Magnetic Resonance Spectroscopy Models, Molecular Peptoids Protein Conformation Somatostatin - analogs & derivatives somatostatin analogs Temperature Time Factors
Online-Zugang:	Volltext
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