Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulates Transepithelial Glucose Transport

The purpose of this study was to characterize the effects of glucose‐dependent insulinotropic peptide (GIP) on small intestinal glucose transport in vitro. Stripped proximal jejunum from fasted mice was mounted in Ussing chambers. The serosal side was bathed in Regular Ringer solution containing 5 m...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2008-11, Vol.16 (11), p.2412-2416
Hauptverfasser:	Singh, Satish K, Bartoo, Aaron C, Krishnan, Selvi, Boylan, Michael O, Schwartz, John H, Wolfe, M. Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	3-O-Methylglucose - metabolism active transport Adenosine adenosine monophosphate animal models animal tissues Animals Cells, Cultured Cyclic AMP - metabolism Dose-Response Relationship, Drug electrophysiology enterocytes Enterocytes - cytology Enterocytes - drug effects Enterocytes - metabolism epithelial cells Gastric Inhibitory Polypeptide - metabolism Gastric Inhibitory Polypeptide - pharmacology Gastrointestinal Agents - metabolism Gastrointestinal Agents - pharmacology Glucose Glucose - metabolism glucose-dependent insulinotropic polypeptide Homeostasis Insulin intercellular spaces intestinal absorption intestinal mucosa jejunum Jejunum - cytology Jejunum - drug effects Jejunum - metabolism Male Mice Mice, Inbred BALB C Obesity - etiology Obesity - metabolism Phlorhizin - pharmacology Physiology Polypeptides Small intestine Sodium-Glucose Transporter 1 - antagonists & inhibitors Sodium-Glucose Transporter 1 - metabolism transport proteins
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