Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy
Objective To investigate the relationship between heart rate variability and hypercapnia. Patients and Methods We measured the coefficient of variation of R-R interval (CVrr) and arterial blood gas pressures in 73 patients with Duchenne muscular dystrophy. Results CVrr was negatively correlated with...
Gespeichert in:
| Veröffentlicht in: | Internal Medicine 2008, Vol.47(21), pp.1893-1897 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1897 |
|---|---|
| container_issue | 21 |
| container_start_page | 1893 |
| container_title | Internal Medicine |
| container_volume | 47 |
| creator | Mochizuki, Hitoshi Okahashi, Satomi Ugawa, Yoshikazu Tamura, Takuhisa Suzuki, Mikiya Miyatake, Satoko Shigeyama, Toshiki Ogata, Katsuhisa Kawai, Mitsuru |
| description | Objective To investigate the relationship between heart rate variability and hypercapnia. Patients and Methods We measured the coefficient of variation of R-R interval (CVrr) and arterial blood gas pressures in 73 patients with Duchenne muscular dystrophy. Results CVrr was negatively correlated with arterial partial pressure of carbon dioxide (PaCO2). In patients whose CVrr was larger than 5%, 84% of them had no hypercapnia while the other 16% had hypercapnia (PaCO2 >45 mmHg). In contrast, 27% of those with CVrr smaller than 3% had no hypercapnia, 73% had hypercapnia and 47% had severe hypercapnia (PaCO2 >50 mmHg). Conclusion We first showed that CVrr was negatively correlated with PaCO2, and propose that abnormally low CVrr indicates respiratory insufficiency in patients with Duchenne muscular dystrophy. |
| doi_str_mv | 10.2169/internalmedicine.47.1118 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69740826</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69740826</sourcerecordid><originalsourceid>FETCH-LOGICAL-c582t-7aeb27e69b9f4e77ff3051a5be59ef1fef35a0470c6299893c59e573d83aec7f3</originalsourceid><addsrcrecordid>eNptkE1r4zAQhkXZ0mbT_oWi096c1YdtSccl_UghJbC0vYqxMmpUHMUr2Qf_-3VJ6MLSywzMPPMOPIRQzhaC1-ZniD2mCO0et8GFiItSLTjn-ozMuCxNoYSsvpEZM1wXYiqX5HvO74xJrYy4IJdcG81rKWfkboWQevobeqSvkAI0oQ39SCFu6WrsMDnoYgAaIr0d3A5jRPo0ZDe0kOjtmPt06HbjFTn30Ga8PvU5ebm_e16uivXm4XH5a124Sou-UICNUFibxvgSlfJesopD1WBl0HOPXlbASsVcLYzRRrppXim51RLQKS_n5Mcxt0uHPwPm3u5Ddti2EPEwZFsbVTIt6gnUR9ClQ84Jve1S2EMaLWf2Q6H9X6Etlf1QOJ3enH4MzbT8d3hyNgGbI_Cee3jDT2DyGFyLXyYLfqpTivwk3Q6SxSj_AiZZkFw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69740826</pqid></control><display><type>article</type><title>Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy</title><source>J-STAGE Free</source><source>MEDLINE</source><creator>Mochizuki, Hitoshi ; Okahashi, Satomi ; Ugawa, Yoshikazu ; Tamura, Takuhisa ; Suzuki, Mikiya ; Miyatake, Satoko ; Shigeyama, Toshiki ; Ogata, Katsuhisa ; Kawai, Mitsuru</creator><creatorcontrib>Mochizuki, Hitoshi ; Okahashi, Satomi ; Ugawa, Yoshikazu ; Tamura, Takuhisa ; Suzuki, Mikiya ; Miyatake, Satoko ; Shigeyama, Toshiki ; Ogata, Katsuhisa ; Kawai, Mitsuru</creatorcontrib><description>Objective To investigate the relationship between heart rate variability and hypercapnia. Patients and Methods We measured the coefficient of variation of R-R interval (CVrr) and arterial blood gas pressures in 73 patients with Duchenne muscular dystrophy. Results CVrr was negatively correlated with arterial partial pressure of carbon dioxide (PaCO2). In patients whose CVrr was larger than 5%, 84% of them had no hypercapnia while the other 16% had hypercapnia (PaCO2 >45 mmHg). In contrast, 27% of those with CVrr smaller than 3% had no hypercapnia, 73% had hypercapnia and 47% had severe hypercapnia (PaCO2 >50 mmHg). Conclusion We first showed that CVrr was negatively correlated with PaCO2, and propose that abnormally low CVrr indicates respiratory insufficiency in patients with Duchenne muscular dystrophy.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.47.1118</identifier><identifier>PMID: 18981633</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Adolescent ; Adult ; Child ; coefficient of variation of the R-R interval ; Duchenne muscular dystrophy ; Electrocardiography - methods ; Electrocardiography - standards ; Heart Rate - physiology ; heart rate variability ; Humans ; hypercapnia ; Hypercapnia - complications ; Hypercapnia - diagnosis ; Hypercapnia - physiopathology ; Muscular Dystrophy, Duchenne - complications ; Muscular Dystrophy, Duchenne - diagnosis ; Muscular Dystrophy, Duchenne - physiopathology ; Young Adult</subject><ispartof>Internal Medicine, 2008, Vol.47(21), pp.1893-1897</ispartof><rights>2008 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c582t-7aeb27e69b9f4e77ff3051a5be59ef1fef35a0470c6299893c59e573d83aec7f3</citedby><cites>FETCH-LOGICAL-c582t-7aeb27e69b9f4e77ff3051a5be59ef1fef35a0470c6299893c59e573d83aec7f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1881,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18981633$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mochizuki, Hitoshi</creatorcontrib><creatorcontrib>Okahashi, Satomi</creatorcontrib><creatorcontrib>Ugawa, Yoshikazu</creatorcontrib><creatorcontrib>Tamura, Takuhisa</creatorcontrib><creatorcontrib>Suzuki, Mikiya</creatorcontrib><creatorcontrib>Miyatake, Satoko</creatorcontrib><creatorcontrib>Shigeyama, Toshiki</creatorcontrib><creatorcontrib>Ogata, Katsuhisa</creatorcontrib><creatorcontrib>Kawai, Mitsuru</creatorcontrib><title>Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Objective To investigate the relationship between heart rate variability and hypercapnia. Patients and Methods We measured the coefficient of variation of R-R interval (CVrr) and arterial blood gas pressures in 73 patients with Duchenne muscular dystrophy. Results CVrr was negatively correlated with arterial partial pressure of carbon dioxide (PaCO2). In patients whose CVrr was larger than 5%, 84% of them had no hypercapnia while the other 16% had hypercapnia (PaCO2 >45 mmHg). In contrast, 27% of those with CVrr smaller than 3% had no hypercapnia, 73% had hypercapnia and 47% had severe hypercapnia (PaCO2 >50 mmHg). Conclusion We first showed that CVrr was negatively correlated with PaCO2, and propose that abnormally low CVrr indicates respiratory insufficiency in patients with Duchenne muscular dystrophy.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Child</subject><subject>coefficient of variation of the R-R interval</subject><subject>Duchenne muscular dystrophy</subject><subject>Electrocardiography - methods</subject><subject>Electrocardiography - standards</subject><subject>Heart Rate - physiology</subject><subject>heart rate variability</subject><subject>Humans</subject><subject>hypercapnia</subject><subject>Hypercapnia - complications</subject><subject>Hypercapnia - diagnosis</subject><subject>Hypercapnia - physiopathology</subject><subject>Muscular Dystrophy, Duchenne - complications</subject><subject>Muscular Dystrophy, Duchenne - diagnosis</subject><subject>Muscular Dystrophy, Duchenne - physiopathology</subject><subject>Young Adult</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1r4zAQhkXZ0mbT_oWi096c1YdtSccl_UghJbC0vYqxMmpUHMUr2Qf_-3VJ6MLSywzMPPMOPIRQzhaC1-ZniD2mCO0et8GFiItSLTjn-ozMuCxNoYSsvpEZM1wXYiqX5HvO74xJrYy4IJdcG81rKWfkboWQevobeqSvkAI0oQ39SCFu6WrsMDnoYgAaIr0d3A5jRPo0ZDe0kOjtmPt06HbjFTn30Ga8PvU5ebm_e16uivXm4XH5a124Sou-UICNUFibxvgSlfJesopD1WBl0HOPXlbASsVcLYzRRrppXim51RLQKS_n5Mcxt0uHPwPm3u5Ddti2EPEwZFsbVTIt6gnUR9ClQ84Jve1S2EMaLWf2Q6H9X6Etlf1QOJ3enH4MzbT8d3hyNgGbI_Cee3jDT2DyGFyLXyYLfqpTivwk3Q6SxSj_AiZZkFw</recordid><startdate>20080101</startdate><enddate>20080101</enddate><creator>Mochizuki, Hitoshi</creator><creator>Okahashi, Satomi</creator><creator>Ugawa, Yoshikazu</creator><creator>Tamura, Takuhisa</creator><creator>Suzuki, Mikiya</creator><creator>Miyatake, Satoko</creator><creator>Shigeyama, Toshiki</creator><creator>Ogata, Katsuhisa</creator><creator>Kawai, Mitsuru</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080101</creationdate><title>Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy</title><author>Mochizuki, Hitoshi ; Okahashi, Satomi ; Ugawa, Yoshikazu ; Tamura, Takuhisa ; Suzuki, Mikiya ; Miyatake, Satoko ; Shigeyama, Toshiki ; Ogata, Katsuhisa ; Kawai, Mitsuru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c582t-7aeb27e69b9f4e77ff3051a5be59ef1fef35a0470c6299893c59e573d83aec7f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Child</topic><topic>coefficient of variation of the R-R interval</topic><topic>Duchenne muscular dystrophy</topic><topic>Electrocardiography - methods</topic><topic>Electrocardiography - standards</topic><topic>Heart Rate - physiology</topic><topic>heart rate variability</topic><topic>Humans</topic><topic>hypercapnia</topic><topic>Hypercapnia - complications</topic><topic>Hypercapnia - diagnosis</topic><topic>Hypercapnia - physiopathology</topic><topic>Muscular Dystrophy, Duchenne - complications</topic><topic>Muscular Dystrophy, Duchenne - diagnosis</topic><topic>Muscular Dystrophy, Duchenne - physiopathology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mochizuki, Hitoshi</creatorcontrib><creatorcontrib>Okahashi, Satomi</creatorcontrib><creatorcontrib>Ugawa, Yoshikazu</creatorcontrib><creatorcontrib>Tamura, Takuhisa</creatorcontrib><creatorcontrib>Suzuki, Mikiya</creatorcontrib><creatorcontrib>Miyatake, Satoko</creatorcontrib><creatorcontrib>Shigeyama, Toshiki</creatorcontrib><creatorcontrib>Ogata, Katsuhisa</creatorcontrib><creatorcontrib>Kawai, Mitsuru</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mochizuki, Hitoshi</au><au>Okahashi, Satomi</au><au>Ugawa, Yoshikazu</au><au>Tamura, Takuhisa</au><au>Suzuki, Mikiya</au><au>Miyatake, Satoko</au><au>Shigeyama, Toshiki</au><au>Ogata, Katsuhisa</au><au>Kawai, Mitsuru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2008-01-01</date><risdate>2008</risdate><volume>47</volume><issue>21</issue><spage>1893</spage><epage>1897</epage><pages>1893-1897</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>Objective To investigate the relationship between heart rate variability and hypercapnia. Patients and Methods We measured the coefficient of variation of R-R interval (CVrr) and arterial blood gas pressures in 73 patients with Duchenne muscular dystrophy. Results CVrr was negatively correlated with arterial partial pressure of carbon dioxide (PaCO2). In patients whose CVrr was larger than 5%, 84% of them had no hypercapnia while the other 16% had hypercapnia (PaCO2 >45 mmHg). In contrast, 27% of those with CVrr smaller than 3% had no hypercapnia, 73% had hypercapnia and 47% had severe hypercapnia (PaCO2 >50 mmHg). Conclusion We first showed that CVrr was negatively correlated with PaCO2, and propose that abnormally low CVrr indicates respiratory insufficiency in patients with Duchenne muscular dystrophy.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>18981633</pmid><doi>10.2169/internalmedicine.47.1118</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2008, Vol.47(21), pp.1893-1897 |
| issn | 0918-2918 1349-7235 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69740826 |
| source | J-STAGE Free; MEDLINE |
| subjects | Adolescent Adult Child coefficient of variation of the R-R interval Duchenne muscular dystrophy Electrocardiography - methods Electrocardiography - standards Heart Rate - physiology heart rate variability Humans hypercapnia Hypercapnia - complications Hypercapnia - diagnosis Hypercapnia - physiopathology Muscular Dystrophy, Duchenne - complications Muscular Dystrophy, Duchenne - diagnosis Muscular Dystrophy, Duchenne - physiopathology Young Adult |
| title | Heart Rate Variability and Hypercapnia in Duchenne Muscular Dystrophy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T23%3A14%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Heart%20Rate%20Variability%20and%20Hypercapnia%20in%20Duchenne%20Muscular%20Dystrophy&rft.jtitle=Internal%20Medicine&rft.au=Mochizuki,%20Hitoshi&rft.date=2008-01-01&rft.volume=47&rft.issue=21&rft.spage=1893&rft.epage=1897&rft.pages=1893-1897&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.47.1118&rft_dat=%3Cproquest_cross%3E69740826%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69740826&rft_id=info:pmid/18981633&rfr_iscdi=true |