Expression of c-erbB Receptors and Ligands in Human Bronchial Mucosa

The epidermal growth factor receptor (EGFR, c-erbB1) plays a pivotal role in maintenance and repair of epithelial tissues; however, little is known about coexpression of c-erbB receptors and their ligands in human bronchial epithelium. We therefore analyzed the expression of these molecules in cultu...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 1999-05, Vol.20 (5), p.914-923
Hauptverfasser:	Polosa, Riccardo, Prosperini, Gaetano, Leir, Shih-Hsing, Holgate, Stephen T, Lackie, Peter M, Davies, Donna E
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Bronchi - metabolism DNA Primers Flow Cytometry Humans Immunohistochemistry Ligands Mucous Membrane - metabolism Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Receptor, ErbB-2 - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism Tumor Cells, Cultured
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