Two Stages of Increased IgA Transfer During Lactation in the Marsupial, Trichosurus vulpecula (Brushtail Possum)

The polymeric Ig receptor (pIgR) and J chain molecules are involved in the transfer of IgA across the mammary gland epithelia into milk. The J chain binds two IgA molecules to form dimeric IgA, and the pIgR transports this complex through epithelial cells. We report here the cloning of the first mar...

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