The Microfracture Technique for the Treatment of Full-Thickness Articular Cartilage Lesions of the Knee: Midterm Results
Purpose The purpose of this study was to determine the effectiveness of the microfracture technique in the treatment of full-thickness articular cartilage lesions of the knee. Methods In this study the midterm results of 90 patients (47 women and 43 men) with focal full-thickness articular cartilage...
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description | Purpose The purpose of this study was to determine the effectiveness of the microfracture technique in the treatment of full-thickness articular cartilage lesions of the knee. Methods In this study the midterm results of 90 patients (47 women and 43 men) with focal full-thickness articular cartilage lesions who had been managed with the microfracture technique are presented. The mean age of our patients was 34.5 years (range, 20 to 58), and 51 right and 39 left knees were treated. All of the articular lesions involved medial femoral condyles. Results On the basis of follow-up at a mean of 68 months (range, 24 to 108 months), mean improvements in Lysholm knee scores (from 54.2 to 84.6 points), Tegner activity scale scores (from 2.6 to 5.2 points), and Oxford knee interrogation scores (from 23.1 to 44.8 points) were observed ( P < .0001). Moreover, there was a strong and significant correlation between functional results and age younger than 35 years, size of defect less than 2 cm2 , non–weight-bearing surface, and body mass index lower than 25 kg/m2 , respectively ( P < .001). Conclusions According to our midterm results, the microfracture technique is quite effective with regard to the improvement of daily activities with a favorable impact on pain relief and better functional results. Furthermore, we found that there was a correlation between functional results and age, size of defect, location of defect, and body mass index as prognostic parameters. Level of Evidence Level IV, therapeutic case series. |
doi_str_mv | 10.1016/j.arthro.2008.06.015 |
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Methods In this study the midterm results of 90 patients (47 women and 43 men) with focal full-thickness articular cartilage lesions who had been managed with the microfracture technique are presented. The mean age of our patients was 34.5 years (range, 20 to 58), and 51 right and 39 left knees were treated. All of the articular lesions involved medial femoral condyles. Results On the basis of follow-up at a mean of 68 months (range, 24 to 108 months), mean improvements in Lysholm knee scores (from 54.2 to 84.6 points), Tegner activity scale scores (from 2.6 to 5.2 points), and Oxford knee interrogation scores (from 23.1 to 44.8 points) were observed ( P < .0001). Moreover, there was a strong and significant correlation between functional results and age younger than 35 years, size of defect less than 2 cm2 , non–weight-bearing surface, and body mass index lower than 25 kg/m2 , respectively ( P < .001). Conclusions According to our midterm results, the microfracture technique is quite effective with regard to the improvement of daily activities with a favorable impact on pain relief and better functional results. Furthermore, we found that there was a correlation between functional results and age, size of defect, location of defect, and body mass index as prognostic parameters. Level of Evidence Level IV, therapeutic case series.</description><identifier>ISSN: 0749-8063</identifier><identifier>EISSN: 1526-3231</identifier><identifier>DOI: 10.1016/j.arthro.2008.06.015</identifier><identifier>PMID: 18971050</identifier><identifier>CODEN: ARTHE3</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Arthroplasty, Subchondral ; Arthroscopy ; Arthroscopy - methods ; Biological and medical sciences ; Cartilage ; Cartilage Diseases - pathology ; Cartilage Diseases - surgery ; Cartilage, Articular - injuries ; Cartilage, Articular - surgery ; Defect ; Endoscopy ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Knee ; Knee Injuries - pathology ; Knee Injuries - rehabilitation ; Knee Injuries - surgery ; Knee Joint - pathology ; Knee Joint - surgery ; Male ; Medical sciences ; Microfracture ; Middle Aged ; Orthopedic surgery ; Orthopedics ; Postoperative Period ; Retrospective Studies ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surveys and Questionnaires ; Treatment ; Weight-Bearing ; Young Adult</subject><ispartof>Arthroscopy, 2008-11, Vol.24 (11), p.1214-1220</ispartof><rights>Arthroscopy Association of North America</rights><rights>2008 Arthroscopy Association of North America</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c445t-73a482a81d2a37203d3b2458bcad0b831c0bc97b0b4d275e68f3a3fac24530aa3</citedby><cites>FETCH-LOGICAL-c445t-73a482a81d2a37203d3b2458bcad0b831c0bc97b0b4d275e68f3a3fac24530aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0749806308005094$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20830736$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18971050$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Asik, Mehmet, M.D</creatorcontrib><creatorcontrib>Ciftci, Feyyaz, M.D</creatorcontrib><creatorcontrib>Sen, Cengiz, M.D</creatorcontrib><creatorcontrib>Erdil, Mehmet, M.D</creatorcontrib><creatorcontrib>Atalar, Atacan, M.D</creatorcontrib><title>The Microfracture Technique for the Treatment of Full-Thickness Articular Cartilage Lesions of the Knee: Midterm Results</title><title>Arthroscopy</title><addtitle>Arthroscopy</addtitle><description>Purpose The purpose of this study was to determine the effectiveness of the microfracture technique in the treatment of full-thickness articular cartilage lesions of the knee. Methods In this study the midterm results of 90 patients (47 women and 43 men) with focal full-thickness articular cartilage lesions who had been managed with the microfracture technique are presented. The mean age of our patients was 34.5 years (range, 20 to 58), and 51 right and 39 left knees were treated. All of the articular lesions involved medial femoral condyles. Results On the basis of follow-up at a mean of 68 months (range, 24 to 108 months), mean improvements in Lysholm knee scores (from 54.2 to 84.6 points), Tegner activity scale scores (from 2.6 to 5.2 points), and Oxford knee interrogation scores (from 23.1 to 44.8 points) were observed ( P < .0001). Moreover, there was a strong and significant correlation between functional results and age younger than 35 years, size of defect less than 2 cm2 , non–weight-bearing surface, and body mass index lower than 25 kg/m2 , respectively ( P < .001). Conclusions According to our midterm results, the microfracture technique is quite effective with regard to the improvement of daily activities with a favorable impact on pain relief and better functional results. Furthermore, we found that there was a correlation between functional results and age, size of defect, location of defect, and body mass index as prognostic parameters. Level of Evidence Level IV, therapeutic case series.</description><subject>Adult</subject><subject>Arthroplasty, Subchondral</subject><subject>Arthroscopy</subject><subject>Arthroscopy - methods</subject><subject>Biological and medical sciences</subject><subject>Cartilage</subject><subject>Cartilage Diseases - pathology</subject><subject>Cartilage Diseases - surgery</subject><subject>Cartilage, Articular - injuries</subject><subject>Cartilage, Articular - surgery</subject><subject>Defect</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Knee</subject><subject>Knee Injuries - pathology</subject><subject>Knee Injuries - rehabilitation</subject><subject>Knee Injuries - surgery</subject><subject>Knee Joint - pathology</subject><subject>Knee Joint - surgery</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microfracture</subject><subject>Middle Aged</subject><subject>Orthopedic surgery</subject><subject>Orthopedics</subject><subject>Postoperative Period</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surveys and Questionnaires</subject><subject>Treatment</subject><subject>Weight-Bearing</subject><subject>Young Adult</subject><issn>0749-8063</issn><issn>1526-3231</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk2LFDEQhoMo7rj6D0Ry0Vu3laQ_0h6EZXBVHBG0PYd0utrJbCa9m6TF_femmUHBi6cc8tRbVQ9FyHMGJQPWvD6UOqR9mEsOIEtoSmD1A7JhNW8KwQV7SDbQVl0hoREX5EmMBwAQQorH5ILJrmVQw4b86vdIP1sT5ilok5aAtEez9_ZuQTrNgab83wfU6Yg-0Xmi14tzRb-35sZjjPQqJGsWpwPd5nms0z-Q7jDa2ceVXss_ecQ3ucmYMBzpV4yLS_EpeTRpF_HZ-b0k36_f9dsPxe7L-4_bq11hqqpORSt0JbmWbORatBzEKAZe1XIweoRBCmZgMF07wFCNvK2xkZPQYtImQwK0Fpfk1Sn3Nsx5p5jU0UaDzmmP8xJV07VCdHWdweoEZhcxBpzUbbBHHe4VA7UaVwd1Mq5W4woalY3nshfn_GU44vi36Kw4Ay_PgI5Gu6zZGxv_cBykgFY0mXt74jDb-GkxqGgseoOjDWiSGmf7v0n-DTDOept73uA9xsO8BJ9NK6YiV6C-rdexHgdIyHN2lfgNjVy2vw</recordid><startdate>20081101</startdate><enddate>20081101</enddate><creator>Asik, Mehmet, M.D</creator><creator>Ciftci, Feyyaz, M.D</creator><creator>Sen, Cengiz, M.D</creator><creator>Erdil, Mehmet, M.D</creator><creator>Atalar, Atacan, M.D</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20081101</creationdate><title>The Microfracture Technique for the Treatment of Full-Thickness Articular Cartilage Lesions of the Knee: Midterm Results</title><author>Asik, Mehmet, M.D ; Ciftci, Feyyaz, M.D ; Sen, Cengiz, M.D ; Erdil, Mehmet, M.D ; Atalar, Atacan, M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c445t-73a482a81d2a37203d3b2458bcad0b831c0bc97b0b4d275e68f3a3fac24530aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Arthroplasty, Subchondral</topic><topic>Arthroscopy</topic><topic>Arthroscopy - methods</topic><topic>Biological and medical sciences</topic><topic>Cartilage</topic><topic>Cartilage Diseases - pathology</topic><topic>Cartilage Diseases - surgery</topic><topic>Cartilage, Articular - injuries</topic><topic>Cartilage, Articular - surgery</topic><topic>Defect</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Knee</topic><topic>Knee Injuries - pathology</topic><topic>Knee Injuries - rehabilitation</topic><topic>Knee Injuries - surgery</topic><topic>Knee Joint - pathology</topic><topic>Knee Joint - surgery</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Microfracture</topic><topic>Middle Aged</topic><topic>Orthopedic surgery</topic><topic>Orthopedics</topic><topic>Postoperative Period</topic><topic>Retrospective Studies</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surveys and Questionnaires</topic><topic>Treatment</topic><topic>Weight-Bearing</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Asik, Mehmet, M.D</creatorcontrib><creatorcontrib>Ciftci, Feyyaz, M.D</creatorcontrib><creatorcontrib>Sen, Cengiz, M.D</creatorcontrib><creatorcontrib>Erdil, Mehmet, M.D</creatorcontrib><creatorcontrib>Atalar, Atacan, M.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Arthroscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Asik, Mehmet, M.D</au><au>Ciftci, Feyyaz, M.D</au><au>Sen, Cengiz, M.D</au><au>Erdil, Mehmet, M.D</au><au>Atalar, Atacan, M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Microfracture Technique for the Treatment of Full-Thickness Articular Cartilage Lesions of the Knee: Midterm Results</atitle><jtitle>Arthroscopy</jtitle><addtitle>Arthroscopy</addtitle><date>2008-11-01</date><risdate>2008</risdate><volume>24</volume><issue>11</issue><spage>1214</spage><epage>1220</epage><pages>1214-1220</pages><issn>0749-8063</issn><eissn>1526-3231</eissn><coden>ARTHE3</coden><abstract>Purpose The purpose of this study was to determine the effectiveness of the microfracture technique in the treatment of full-thickness articular cartilage lesions of the knee. Methods In this study the midterm results of 90 patients (47 women and 43 men) with focal full-thickness articular cartilage lesions who had been managed with the microfracture technique are presented. The mean age of our patients was 34.5 years (range, 20 to 58), and 51 right and 39 left knees were treated. All of the articular lesions involved medial femoral condyles. Results On the basis of follow-up at a mean of 68 months (range, 24 to 108 months), mean improvements in Lysholm knee scores (from 54.2 to 84.6 points), Tegner activity scale scores (from 2.6 to 5.2 points), and Oxford knee interrogation scores (from 23.1 to 44.8 points) were observed ( P < .0001). Moreover, there was a strong and significant correlation between functional results and age younger than 35 years, size of defect less than 2 cm2 , non–weight-bearing surface, and body mass index lower than 25 kg/m2 , respectively ( P < .001). Conclusions According to our midterm results, the microfracture technique is quite effective with regard to the improvement of daily activities with a favorable impact on pain relief and better functional results. Furthermore, we found that there was a correlation between functional results and age, size of defect, location of defect, and body mass index as prognostic parameters. Level of Evidence Level IV, therapeutic case series.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18971050</pmid><doi>10.1016/j.arthro.2008.06.015</doi><tpages>7</tpages></addata></record> |
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subjects | Adult Arthroplasty, Subchondral Arthroscopy Arthroscopy - methods Biological and medical sciences Cartilage Cartilage Diseases - pathology Cartilage Diseases - surgery Cartilage, Articular - injuries Cartilage, Articular - surgery Defect Endoscopy Female Humans Investigative techniques, diagnostic techniques (general aspects) Knee Knee Injuries - pathology Knee Injuries - rehabilitation Knee Injuries - surgery Knee Joint - pathology Knee Joint - surgery Male Medical sciences Microfracture Middle Aged Orthopedic surgery Orthopedics Postoperative Period Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surveys and Questionnaires Treatment Weight-Bearing Young Adult |
title | The Microfracture Technique for the Treatment of Full-Thickness Articular Cartilage Lesions of the Knee: Midterm Results |
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