Improvement of brain tissue oxygenation by inhalation of carbogen

Abstract Hyperoxic therapy for cerebral ischemia is suspected to reduce cerebral blood flow (CBF), due to the vasoconstrictive effect of oxygen on cerebral arterioles. We hypothesized that vasodilation predominates when 5% CO2 is added to the inhaled oxygen (carbogen). Therefore, we used positron em...

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Veröffentlicht in:	Neuroscience 2008-10, Vol.156 (4), p.932-938
Hauptverfasser:	Ashkanian, M, Borghammer, P, Gjedde, A, Østergaard, L, Vafaee, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Blood Flow Velocity Blood Gas Analysis Brain - anatomy & histology Brain - diagnostic imaging Brain - metabolism Brain Chemistry Brain Mapping brain tissue oxygenation carbogen Carbon Dioxide - administration & dosage CBF Cerebrovascular Circulation - physiology Female Fundamental and applied biological sciences. Psychology Humans Inhalation Magnetic Resonance Imaging - methods Male Middle Aged Neurology OEF oxygen Oxygen - administration & dosage Oxygen Radioisotopes - metabolism Positron-Emission Tomography Radiation-Sensitizing Agents - administration & dosage Vertebrates: nervous system and sense organs
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