β-Alanine and the Hormonal Response to Exercise
Abstract The effect of 30 days of β-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of...
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Veröffentlicht in: | International journal of sports medicine 2008-12, Vol.29 (12), p.952-958 |
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creator | Hoffman, J. Ratamess, N. A. Ross, R. Kang, J. Magrelli, J. Neese, K. Faigenbaum, A. D. Wise, J. A. |
description | Abstract
The effect of 30 days of β-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with 1.5 minutes of rest between sets was performed before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (IP), 15-minutes (15P) and 30-minutes (30P) postexercise for growth hormone, testosterone and cortisol concentrations. A 22 % (p |
doi_str_mv | 10.1055/s-2008-1038678 |
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The effect of 30 days of β-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with 1.5 minutes of rest between sets was performed before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (IP), 15-minutes (15P) and 30-minutes (30P) postexercise for growth hormone, testosterone and cortisol concentrations. A 22 % (p < 0.05) difference in total number of repetitions performed at the end of 4 weeks of supplementation was seen between β-alanine (BA) and placebo (PL), and Δ mean power was greater in BA (98.4 ± 43.8 w) vs. PL (7.2 ± 29.6 w). Growth hormone concentrations were elevated from BL at IP and 15P for both groups, while cortisol concentrations were greater than BL at all time points for both BA and PL. No group differences were noted. No change from BL was seen in testosterone concentrations for either group. Results indicate that four weeks of β-alanine supplementation can significantly improve muscular endurance during resistance training in experienced resistance-trained athletes. However, these performance gains did not affect the acute endocrine response to the exercise stimulus.</description><identifier>ISSN: 0172-4622</identifier><identifier>EISSN: 1439-3964</identifier><identifier>DOI: 10.1055/s-2008-1038678</identifier><identifier>PMID: 18548362</identifier><identifier>CODEN: IJSMDA</identifier><language>eng</language><publisher>Stuttgart: Thieme</publisher><subject>Adaptation, Physiological - physiology ; Adult ; beta-Alanine - pharmacology ; beta-Alanine - therapeutic use ; Biological and medical sciences ; Cross-Over Studies ; Dietary Supplements ; Double-Blind Method ; Exercise - physiology ; Exercise Test ; Fundamental and applied biological sciences. Psychology ; Growth Hormone - blood ; Humans ; Hydrocortisone - blood ; Male ; Muscle Contraction - physiology ; Muscle Strength - physiology ; Muscle, Skeletal - physiology ; Physiology & Biochemistry ; Sex Factors ; Testosterone - blood ; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</subject><ispartof>International journal of sports medicine, 2008-12, Vol.29 (12), p.952-958</ispartof><rights>Georg Thieme Verlag KG Stuttgart · New York</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-df2282b833e16e7faeaeab216f6529bb2317a6e678ca9d19f2d895ce6108087a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2008-1038678.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/s-2008-1038678$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,777,781,3004,3005,27905,27906,54540,54541</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20876925$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18548362$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hoffman, J.</creatorcontrib><creatorcontrib>Ratamess, N. A.</creatorcontrib><creatorcontrib>Ross, R.</creatorcontrib><creatorcontrib>Kang, J.</creatorcontrib><creatorcontrib>Magrelli, J.</creatorcontrib><creatorcontrib>Neese, K.</creatorcontrib><creatorcontrib>Faigenbaum, A. D.</creatorcontrib><creatorcontrib>Wise, J. A.</creatorcontrib><title>β-Alanine and the Hormonal Response to Exercise</title><title>International journal of sports medicine</title><addtitle>Int J Sports Med</addtitle><description>Abstract
The effect of 30 days of β-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with 1.5 minutes of rest between sets was performed before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (IP), 15-minutes (15P) and 30-minutes (30P) postexercise for growth hormone, testosterone and cortisol concentrations. A 22 % (p < 0.05) difference in total number of repetitions performed at the end of 4 weeks of supplementation was seen between β-alanine (BA) and placebo (PL), and Δ mean power was greater in BA (98.4 ± 43.8 w) vs. PL (7.2 ± 29.6 w). Growth hormone concentrations were elevated from BL at IP and 15P for both groups, while cortisol concentrations were greater than BL at all time points for both BA and PL. No group differences were noted. No change from BL was seen in testosterone concentrations for either group. Results indicate that four weeks of β-alanine supplementation can significantly improve muscular endurance during resistance training in experienced resistance-trained athletes. However, these performance gains did not affect the acute endocrine response to the exercise stimulus.</description><subject>Adaptation, Physiological - physiology</subject><subject>Adult</subject><subject>beta-Alanine - pharmacology</subject><subject>beta-Alanine - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cross-Over Studies</subject><subject>Dietary Supplements</subject><subject>Double-Blind Method</subject><subject>Exercise - physiology</subject><subject>Exercise Test</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Growth Hormone - blood</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Male</subject><subject>Muscle Contraction - physiology</subject><subject>Muscle Strength - physiology</subject><subject>Muscle, Skeletal - physiology</subject><subject>Physiology & Biochemistry</subject><subject>Sex Factors</subject><subject>Testosterone - blood</subject><subject>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</subject><issn>0172-4622</issn><issn>1439-3964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kL9OwzAQhy0EoqWwMqIssLn4T-LYY1UVilQJCcFsOclZTZXExU4keC0ehGfCVSOY0A23fHf3uw-ha0rmlGTZfcCMEIkp4VLk8gRNacoV5kqkp2hKaM5wKhiboIsQdoTQVFF-jiZUZqnkgk0R-f7Ci8Z0dQeJ6aqk30Kydr51nWmSFwh71wVIepesPsCXdYBLdGZNE-Bq7DP09rB6Xa7x5vnxabnY4JIL2uPKMiZZITkHKiC3BmIVjAorMqaKgnGaGwExc2lURZVllVRZCYISSWRu-AzdHffuvXsfIPS6rUMJTcwKbghaqJwpTngE50ew9C4ED1bvfd0a_6kp0QdHOuiDIz06igM34-ahaKH6w0cpEbgdARNK01hvuvj5L8diPqFYFjl85PptDS3onRt81Bb-O_wDeDR7ow</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>Hoffman, J.</creator><creator>Ratamess, N. A.</creator><creator>Ross, R.</creator><creator>Kang, J.</creator><creator>Magrelli, J.</creator><creator>Neese, K.</creator><creator>Faigenbaum, A. D.</creator><creator>Wise, J. A.</creator><general>Thieme</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20081201</creationdate><title>β-Alanine and the Hormonal Response to Exercise</title><author>Hoffman, J. ; Ratamess, N. A. ; Ross, R. ; Kang, J. ; Magrelli, J. ; Neese, K. ; Faigenbaum, A. D. ; Wise, J. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-df2282b833e16e7faeaeab216f6529bb2317a6e678ca9d19f2d895ce6108087a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adaptation, Physiological - physiology</topic><topic>Adult</topic><topic>beta-Alanine - pharmacology</topic><topic>beta-Alanine - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cross-Over Studies</topic><topic>Dietary Supplements</topic><topic>Double-Blind Method</topic><topic>Exercise - physiology</topic><topic>Exercise Test</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Growth Hormone - blood</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Male</topic><topic>Muscle Contraction - physiology</topic><topic>Muscle Strength - physiology</topic><topic>Muscle, Skeletal - physiology</topic><topic>Physiology & Biochemistry</topic><topic>Sex Factors</topic><topic>Testosterone - blood</topic><topic>Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hoffman, J.</creatorcontrib><creatorcontrib>Ratamess, N. A.</creatorcontrib><creatorcontrib>Ross, R.</creatorcontrib><creatorcontrib>Kang, J.</creatorcontrib><creatorcontrib>Magrelli, J.</creatorcontrib><creatorcontrib>Neese, K.</creatorcontrib><creatorcontrib>Faigenbaum, A. D.</creatorcontrib><creatorcontrib>Wise, J. A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hoffman, J.</au><au>Ratamess, N. A.</au><au>Ross, R.</au><au>Kang, J.</au><au>Magrelli, J.</au><au>Neese, K.</au><au>Faigenbaum, A. D.</au><au>Wise, J. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>β-Alanine and the Hormonal Response to Exercise</atitle><jtitle>International journal of sports medicine</jtitle><addtitle>Int J Sports Med</addtitle><date>2008-12-01</date><risdate>2008</risdate><volume>29</volume><issue>12</issue><spage>952</spage><epage>958</epage><pages>952-958</pages><issn>0172-4622</issn><eissn>1439-3964</eissn><coden>IJSMDA</coden><abstract>Abstract
The effect of 30 days of β-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with 1.5 minutes of rest between sets was performed before and after each supplemental period. Blood draws occurred at baseline (BL), immediate (IP), 15-minutes (15P) and 30-minutes (30P) postexercise for growth hormone, testosterone and cortisol concentrations. A 22 % (p < 0.05) difference in total number of repetitions performed at the end of 4 weeks of supplementation was seen between β-alanine (BA) and placebo (PL), and Δ mean power was greater in BA (98.4 ± 43.8 w) vs. PL (7.2 ± 29.6 w). Growth hormone concentrations were elevated from BL at IP and 15P for both groups, while cortisol concentrations were greater than BL at all time points for both BA and PL. No group differences were noted. No change from BL was seen in testosterone concentrations for either group. Results indicate that four weeks of β-alanine supplementation can significantly improve muscular endurance during resistance training in experienced resistance-trained athletes. However, these performance gains did not affect the acute endocrine response to the exercise stimulus.</abstract><cop>Stuttgart</cop><pub>Thieme</pub><pmid>18548362</pmid><doi>10.1055/s-2008-1038678</doi><tpages>7</tpages></addata></record> |
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subjects | Adaptation, Physiological - physiology Adult beta-Alanine - pharmacology beta-Alanine - therapeutic use Biological and medical sciences Cross-Over Studies Dietary Supplements Double-Blind Method Exercise - physiology Exercise Test Fundamental and applied biological sciences. Psychology Growth Hormone - blood Humans Hydrocortisone - blood Male Muscle Contraction - physiology Muscle Strength - physiology Muscle, Skeletal - physiology Physiology & Biochemistry Sex Factors Testosterone - blood Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports |
title | β-Alanine and the Hormonal Response to Exercise |
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