Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner

Common sites of breast cancer metastasis include the lung, liver, and bone, and of these secondary metastatic sites, estrogen receptor alpha (ERalpha)-positive breast cancer often favors bone. Within secondary organs, cancer cells would predictably encounter tissue-specific fibroblasts or their solu...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2008-11, Vol.68 (21), p.9087-9095
Hauptverfasser:	Studebaker, Adam W, Storci, Gianluca, Werbeck, Jillian L, Sansone, Pasquale, Sasser, A Kate, Tavolari, Simona, Huang, Tim, Chan, Michael W Y, Marini, Frank C, Rosol, Thomas J, Bonafé, Massimiliano, Hall, Brett M
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Division - physiology Cell Line, Tumor Culture Media, Conditioned Fibroblasts - cytology Humans Immunoprecipitation Interleukin-6 - physiology Neoplasm Invasiveness Neoplasm Metastasis Phosphorylation RNA Interference STAT3 Transcription Factor - metabolism
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