The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma

Tumor perineural dissemination is a hallmark of human pancreatic ductal adenocarcinoma (PDAC) and represents a major source of local tumor recurrence after surgery. In this study, we provide in vitro and in vivo evidence that the chemokine receptor CX3CR1 may be involved in the neurotropism of PDAC...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2008-11, Vol.68 (21), p.9060-9069
Hauptverfasser:	Marchesi, Federica, Piemonti, Lorenzo, Fedele, Giuseppe, Destro, Annarita, Roncalli, Massimo, Albarello, Luca, Doglioni, Claudio, Anselmo, Achille, Doni, Andrea, Bianchi, Paolo, Laghi, Luigi, Malesci, Alberto, Cervo, Luigi, Malosio, Marialuisa, Reni, Michele, Zerbi, Alessandro, Di Carlo, Valerio, Mantovani, Alberto, Allavena, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Animals Cell Adhesion Cell Line, Tumor Chemotaxis CX3C Chemokine Receptor 1 GTP-Binding Proteins - physiology Humans Immunohistochemistry Integrin beta1 - physiology Mice Microscopy, Confocal Nervous System - pathology Pancreatic Neoplasms - pathology Receptors, Chemokine - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!