Prevention of Experimental Antiphospholipid Syndrome and Endothelial Cell Activation by Synthetic Peptides

Antiphospholipid syndrome (APS) is characterized by recurrent fetal loss, repeated thromboembolic phenomena, and thrombocytopenia. The syndrome is believed to be caused by antiphospholipid beta-2-glycoprotein-I (β 2GPI)-dependent Abs or anti-β 2GPI Abs by themselves. Using a hexapeptide phage displa...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1999-04, Vol.96 (9), p.5164-5168
Hauptverfasser:	Blank, Miri, Shoenfeld, Yehuda, Cabilly, Shmuel, Heldman, Yehudit, Fridkin, Mati, Katchalski-Katzir, Ephrajm
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Animals Antibodies, Monoclonal - immunology Antibody Specificity Antiphospholipid syndrome Antiphospholipid Syndrome - immunology Antiphospholipid Syndrome - prevention & control Bacteriophages beta 2-Glycoprotein I Biological Sciences Endothelial cells Endothelium, Vascular - drug effects Endothelium, Vascular - immunology Epitopes Epitopes - immunology Glycoproteins - immunology Humans Immunology Libraries Mice Mice, Inbred BALB C Molecules Monocytes Partial thromboplastin time Peptides Peptides - administration & dosage Peptides - immunology Platelets
Online-Zugang:	Volltext
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