The Future of Molecular Genetic Testing
The potential applications for genetic testing are immense, with most diseases having some aspect influenced by, if not directly caused by, changes in the genome of the patient. The translation of genetic information into medical applications will be influenced by our understanding of the human geno...
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| Veröffentlicht in: | Clinical chemistry (Baltimore, Md.) Md.), 1999-05, Vol.45 (5), p.726-731 |
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| container_title | Clinical chemistry (Baltimore, Md.) |
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| creator | Leonard, Debra G.B |
| description | The potential applications for genetic testing are immense, with most diseases having some aspect influenced by, if not directly caused by, changes in the genome of the patient. The translation of genetic information into medical applications will be influenced by our understanding of the human genome, technological advances, and social, ethical, and legal issues surrounding genetic testing. With time, new genetic information will be translated into clinical tests for the diagnosis of current illness and prediction of future disease risk, and will be used for the development of genetically directed therapies and preventive interventions. Most genetic testing will be highly automated, with only rare genetic disease tests performed manually. The challenge for the clinical genetic laboratory is to keep pace with this information explosion to provide state-of-the-art genetic testing and to ensure that the genetic test results are used in a morally, ethically, and socially responsible way. |
| doi_str_mv | 10.1093/clinchem/45.5.726 |
| format | Article |
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The translation of genetic information into medical applications will be influenced by our understanding of the human genome, technological advances, and social, ethical, and legal issues surrounding genetic testing. With time, new genetic information will be translated into clinical tests for the diagnosis of current illness and prediction of future disease risk, and will be used for the development of genetically directed therapies and preventive interventions. Most genetic testing will be highly automated, with only rare genetic disease tests performed manually. 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The translation of genetic information into medical applications will be influenced by our understanding of the human genome, technological advances, and social, ethical, and legal issues surrounding genetic testing. With time, new genetic information will be translated into clinical tests for the diagnosis of current illness and prediction of future disease risk, and will be used for the development of genetically directed therapies and preventive interventions. Most genetic testing will be highly automated, with only rare genetic disease tests performed manually. The challenge for the clinical genetic laboratory is to keep pace with this information explosion to provide state-of-the-art genetic testing and to ensure that the genetic test results are used in a morally, ethically, and socially responsible way.</description><subject>Biological and medical sciences</subject><subject>DNA - genetics</subject><subject>DNA Mutational Analysis - methods</subject><subject>Ethics, Medical</subject><subject>General aspects. Genetic counseling</subject><subject>Genetics, Medical - legislation & jurisprudence</subject><subject>Genetics, Medical - methods</subject><subject>Genome, Human</subject><subject>Human Genome Project</subject><subject>Humans</subject><subject>Medical genetics</subject><subject>Medical sciences</subject><subject>Patents as Topic</subject><issn>0009-9147</issn><issn>1530-8561</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkElPwzAUhC0EoqXwA7igHFhOab1mOaKKFqQiLuVs2c5LE-QkxU4U8e9JlbKcnkb6ZkZvELomeE5wyhbGlrUpoFpwMRfzmEYnaEoEw2EiInKKphjjNEwJjyfowvuPQfI4ic7RhGBKKYv5FD1sCwhWXds5CJo8eG0smM4qF6yhhrY0wRZ8W9a7S3SWK-vh6nhn6H31tF0-h5u39cvycRMalqZtSDCOKAYMhBBOSSQMi3PMtY51pJSm2mSRzrlgyqSZBoJ1LEBxzjNFE8qBzdD9mLt3zWc3dMuq9AasVTU0nZdROrxJKBtAMoLGNd47yOXelZVyX5JgeVhH_qwjuZBCDrbBc3MM73QF2T_HOMcA3B4B5Y2yuVO1Kf0flwiWsAN2N2JFuSv60oH0lbJ2SCWy7_vfvm9cM3qI</recordid><startdate>19990501</startdate><enddate>19990501</enddate><creator>Leonard, Debra G.B</creator><general>Am Assoc Clin Chem</general><general>American Association for Clinical Chemistry</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990501</creationdate><title>The Future of Molecular Genetic Testing</title><author>Leonard, Debra G.B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-100620e0e11142165c37f04bb7b6aab2bcd6bf453ac9dbe10b75ea444da2824e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Biological and medical sciences</topic><topic>DNA - genetics</topic><topic>DNA Mutational Analysis - methods</topic><topic>Ethics, Medical</topic><topic>General aspects. 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| ispartof | Clinical chemistry (Baltimore, Md.), 1999-05, Vol.45 (5), p.726-731 |
| issn | 0009-9147 1530-8561 |
| language | eng |
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| source | MEDLINE; Oxford Academic Journals (OUP) |
| subjects | Biological and medical sciences DNA - genetics DNA Mutational Analysis - methods Ethics, Medical General aspects. Genetic counseling Genetics, Medical - legislation & jurisprudence Genetics, Medical - methods Genome, Human Human Genome Project Humans Medical genetics Medical sciences Patents as Topic |
| title | The Future of Molecular Genetic Testing |
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