Helicobacter pylori and Nonulcer Dyspepsia
To the Editor: McColl et al. and Blum et al. (Dec. 24 issue) 1 , 2 reached opposite conclusions regarding the eradication of Helicobacter pylori infection in patients with nonulcer dyspepsia. In an accompanying editorial, Friedman 3 concluded that breakthroughs in the treatment of nonulcer dyspepsia...
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Veröffentlicht in: | The New England journal of medicine 1999-05, Vol.340 (19), p.1508-1511 |
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creator | Lieber, C S |
description | To the Editor:
McColl et al. and Blum et al. (Dec. 24 issue)
1
,
2
reached opposite conclusions regarding the eradication of
Helicobacter pylori
infection in patients with nonulcer dyspepsia. In an accompanying editorial, Friedman
3
concluded that breakthroughs in the treatment of nonulcer dyspepsia will probably result from basic investigations into visceral sensitivity and brain–gut interactions rather than from further examination of the role of
H. pylori
infection.
Nonulcer dyspepsia is a heterogeneous condition. It is conceivable that the two studies involved somewhat different groups of patients with different sensitivities to antibiotic treatment. Indeed, one subgroup of patients with nonulcer dyspepsia . . . |
doi_str_mv | 10.1056/NEJM199905133401912 |
format | Article |
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McColl et al. and Blum et al. (Dec. 24 issue)
1
,
2
reached opposite conclusions regarding the eradication of
Helicobacter pylori
infection in patients with nonulcer dyspepsia. In an accompanying editorial, Friedman
3
concluded that breakthroughs in the treatment of nonulcer dyspepsia will probably result from basic investigations into visceral sensitivity and brain–gut interactions rather than from further examination of the role of
H. pylori
infection.
Nonulcer dyspepsia is a heterogeneous condition. It is conceivable that the two studies involved somewhat different groups of patients with different sensitivities to antibiotic treatment. Indeed, one subgroup of patients with nonulcer dyspepsia . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199905133401912</identifier><identifier>PMID: 10328715</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Alcoholism - complications ; Anti-Bacterial Agents - therapeutic use ; Dyspepsia - drug therapy ; Dyspepsia - microbiology ; Gastritis - drug therapy ; Gastritis - etiology ; Helicobacter Infections - drug therapy ; Helicobacter pylori ; Humans</subject><ispartof>The New England journal of medicine, 1999-05, Vol.340 (19), p.1508-1511</ispartof><rights>Copyright © 1999 Massachusetts Medical Society. All rights reserved.</rights><rights>Copyright National Library of Medicine - MEDLINE Abstracts May 13 1999</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c461t-d7a2a80f12e998c119bba1c8164dcb629c3527a3f238e2310ab3d03d620b34003</citedby><cites>FETCH-LOGICAL-c461t-d7a2a80f12e998c119bba1c8164dcb629c3527a3f238e2310ab3d03d620b34003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199905133401912$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199905133401912$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10328715$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lieber, C S</creatorcontrib><title>Helicobacter pylori and Nonulcer Dyspepsia</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
McColl et al. and Blum et al. (Dec. 24 issue)
1
,
2
reached opposite conclusions regarding the eradication of
Helicobacter pylori
infection in patients with nonulcer dyspepsia. In an accompanying editorial, Friedman
3
concluded that breakthroughs in the treatment of nonulcer dyspepsia will probably result from basic investigations into visceral sensitivity and brain–gut interactions rather than from further examination of the role of
H. pylori
infection.
Nonulcer dyspepsia is a heterogeneous condition. It is conceivable that the two studies involved somewhat different groups of patients with different sensitivities to antibiotic treatment. Indeed, one subgroup of patients with nonulcer dyspepsia . . .</description><subject>Alcoholism - complications</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Dyspepsia - drug therapy</subject><subject>Dyspepsia - microbiology</subject><subject>Gastritis - drug therapy</subject><subject>Gastritis - etiology</subject><subject>Helicobacter Infections - drug therapy</subject><subject>Helicobacter pylori</subject><subject>Humans</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkM1LAzEQxYMoWqt_gSDFgwdldSYfu8lRarVKrRc9h2w2hS37ZdI99L83sj2IiM5lYPi9x7xHyBnCDYJIb5ez5xdUSoFAxjigQrpHRigYSziHdJ-MAKhMeKbYETkOYQ1xkKtDcoTAqMxQjMjV3FWlbXNjN85Pum3V-nJimmKybJu-svF2vw2d60JpTsjBylTBne72mLw_zN6m82Tx-vg0vVsklqe4SYrMUCNhhdQpJS2iynODVmLKC5unVFkmaGbYijLpKEMwOSuAFSmFPMYANiaXg2_n24_ehY2uy2BdVZnGtX3QqcqoEDHmmFz8ANdt75v4m6aUKS65kP9CkCmMEBsg69sQvFvpzpe18VuNoL_K1r-UHVXnO-s-r13xTTO0G4HrAajroBu3rv-0-wSdE4Ke</recordid><startdate>19990513</startdate><enddate>19990513</enddate><creator>Lieber, C S</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>19990513</creationdate><title>Helicobacter pylori and Nonulcer Dyspepsia</title><author>Lieber, C S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-d7a2a80f12e998c119bba1c8164dcb629c3527a3f238e2310ab3d03d620b34003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Alcoholism - complications</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Dyspepsia - drug therapy</topic><topic>Dyspepsia - microbiology</topic><topic>Gastritis - drug therapy</topic><topic>Gastritis - etiology</topic><topic>Helicobacter Infections - drug therapy</topic><topic>Helicobacter pylori</topic><topic>Humans</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lieber, C S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lieber, C S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Helicobacter pylori and Nonulcer Dyspepsia</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1999-05-13</date><risdate>1999</risdate><volume>340</volume><issue>19</issue><spage>1508</spage><epage>1511</epage><pages>1508-1511</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>To the Editor:
McColl et al. and Blum et al. (Dec. 24 issue)
1
,
2
reached opposite conclusions regarding the eradication of
Helicobacter pylori
infection in patients with nonulcer dyspepsia. In an accompanying editorial, Friedman
3
concluded that breakthroughs in the treatment of nonulcer dyspepsia will probably result from basic investigations into visceral sensitivity and brain–gut interactions rather than from further examination of the role of
H. pylori
infection.
Nonulcer dyspepsia is a heterogeneous condition. It is conceivable that the two studies involved somewhat different groups of patients with different sensitivities to antibiotic treatment. Indeed, one subgroup of patients with nonulcer dyspepsia . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>10328715</pmid><doi>10.1056/NEJM199905133401912</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Alcoholism - complications Anti-Bacterial Agents - therapeutic use Dyspepsia - drug therapy Dyspepsia - microbiology Gastritis - drug therapy Gastritis - etiology Helicobacter Infections - drug therapy Helicobacter pylori Humans |
title | Helicobacter pylori and Nonulcer Dyspepsia |
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