Stereotactic Radiosurgery: The Role of Charged Particles

Stereotactic radiosurgery using charged-particle beams has been the subject of biomedical research and clinical development for more than 50 years. Charged particles of proton mass or greater manifest unique physical properties that can be used to place a high dose of radiation preferentially within...

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Veröffentlicht in:Acta oncologica 1999, Vol.38 (2), p.165-169
Hauptverfasser: LEVY, R. P, SCHULTE, R. W. M, SLATER, J. D, MILLER, D. W, SLATER, J. M
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container_start_page 165
container_title Acta oncologica
container_volume 38
creator LEVY, R. P
SCHULTE, R. W. M
SLATER, J. D
MILLER, D. W
SLATER, J. M
description Stereotactic radiosurgery using charged-particle beams has been the subject of biomedical research and clinical development for more than 50 years. Charged particles of proton mass or greater manifest unique physical properties that can be used to place a high dose of radiation preferentially within the boundaries of a deeply located intracranial target volume. Since 1954, nearly 10000 patients have been treated using this technique. Treated disorders include pituitary tumors, vascular malformations, primary and metastatic brain tumors, and subfoveal neovascularization. Charged-particle radiosurgery is particularly advantageous for the conformal treatment of large and/or irregularly shaped lesions, or for the treatment of lesions located in front of or adjacent to sensitive brain structures.
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source MEDLINE; Access via Taylor & Francis; EZB-FREE-00999 freely available EZB journals
subjects Biological and medical sciences
Brain Neoplasms - surgery
Humans
Intracranial Arteriovenous Malformations - surgery
Macular Degeneration - surgery
Medical sciences
Pituitary Gland - surgery
Radiation therapy and radiosensitizing agent
Radiosurgery - methods
Radiotherapy Dosage
Treatment with physical agents
Treatment. General aspects
Tumors
title Stereotactic Radiosurgery: The Role of Charged Particles
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