Group-Specific Assays That Distinguish between the Four Major Types of Mammalian Phospholipase A2

Phospholipase A2(PLA2) constitutes a diverse superfamily of enzymes which catalyze the deacylation of phospholipids. At least four types of PLA2are potentially involved in arachidonic acid release in cells and tissues. Since all of them catalyze the same enzymatic reaction, it is difficult to distin...

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Veröffentlicht in:	Analytical biochemistry 1999-05, Vol.269 (2), p.278-288
Hauptverfasser:	Yang, Hsiu-Chiung, Mosior, Marian, Johnson, Christina A., Chen, Yijun, Dennis, Edward A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - enzymology Cell Line Enzyme Inhibitors - pharmacology Humans Macrophages - enzymology Microchemistry Phospholipases A - analysis Phospholipases A - antagonists & inhibitors Phospholipases A - classification Phospholipases A2 Rats Sensitivity and Specificity
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