Relationship between HLA-DQ and -DR genotypes and clinical characteristics in a French population of Type 1 diabetic patients

Summary Aims The present study was designed to look for a heterogeneity in the association between Type 1 diabetes mellitus (DM) and class II alleles of major histocompatibility complex (MHC) according to clinical presentation and C‐peptide secretion during the first year of the disease, in a popula...

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Veröffentlicht in:	Diabetic medicine 1999-03, Vol.16 (3), p.201-206
Hauptverfasser:	Zevaco-Mattei, C., Reviron, D., Atlan-Gepner, C., Botti, G., Simonin, G., Lassmann-Vague, V., Vague, P., Mercier, P., Vialettes, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Alleles Analysis of Variance Biological and medical sciences C-peptide Child Child, Preschool Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - immunology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female France Genes, MHC Class II Genotype Haplotypes HLA-DQ HLA-DQ Antigens - genetics HLA-DR HLA-DR Antigens - genetics Humans Hypoglycemic Agents - therapeutic use Insulin - metabolism Insulin - therapeutic use Insulin Secretion major histocompatibility complex Male Medical sciences Phenotype Polymorphism, Genetic Type 1 diabetes mellitus
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