An Integrated Microfabricated Device for Dual Microdialysis and On-Line ESI-Ion Trap Mass Spectrometry for Analysis of Complex Biological Samples

A microfabricated dual-microdialysis device in a single integrated microfabricated platform was constructed using laser micromachining techniques for the rapid fractionation and cleanup of complex biological samples. On-line dual microdialysis and ESI-MS of biological samples was demonstrated using...

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Veröffentlicht in:	Analytical Chemistry 1999-04, Vol.71 (8), p.1485-1490
Hauptverfasser:	Xiang, Fan, Lin, Yuehe, Wen, Jenny, Matson, Dean W, Smith, Richard D
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical biochemistry: general aspects, technics, instrumentation Analytical, structural and metabolic biochemistry BASIC BIOLOGICAL SCIENCES Biological and medical sciences BIOLOGICAL MATERIALS Chemistry DESIGN DIALYSIS Escherichia coli - chemistry Experiments FRACTIONATION Fundamental and applied biological sciences. Psychology INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY MASS SPECTROMETRY Mass Spectrometry - instrumentation MASS SPECTROSCOPY MEASURING INSTRUMENTS MICROANALYSIS MICRODIALYSIS Microdialysis - instrumentation MICROFABRICATION Microprocessors MINIATURIZATION Molecular Weight Online Systems
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