Effects of Immune Complex Formation and Complement Activation on Circulating Platelets in the Primate

Primate platelets are different from rodent and rabbit platelets in that they do not express receptors for C3a or C5a or immune adherence receptors. This study assessed the effects of immune complex (IC)-induced complement activation on primate platelets in the circulation. Cynomolgus monkeys (CYN,N...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 1999-04, Vol.91 (1), p.99-105
Hauptverfasser:	Birmingham, Daniel J., Hebert, Lee A., Shen, Xiao-Ping, Higgins, Paul, Yeh, C.Grace, Creasey, Abla A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-Antibody Complex - biosynthesis Antigen-Antibody Complex - blood Biological and medical sciences Blood Cell Count Blood Platelets - immunology Cattle complement Complement Activation Complement C3a - metabolism Experimental and animal immunopathology. Animal models gamma-Globulins - administration & dosage gamma-Globulins - immunology immune complexes Immunization Immunopathology Macaca fascicularis - blood Macaca fascicularis - immunology Medical sciences Mice Platelet Count primate platelets Rabbits Rats Species Specificity
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