Identification and Partial Characterization of an Unusual Distribution of the Photosensitizer meta-Tetrahydroxyphenyl Chlorin (Temoporfin) in Human Plasma

— Temoporfin (m‐THPC) is an extremely powerful photosensitizing drug, more than 100‐fold more photocytotoxic than Photofrin and many other drugs. The reasons for this are not yet known but are likely to be associated with the mechanism of uptake of the drug and its intratumoral and intracellular loc...

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Veröffentlicht in:	Photochemistry and photobiology 1999-04, Vol.69 (4), p.482-488
Hauptverfasser:	Hopkinson, Hazel J., Vernon, David I., Brown, Stanley B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Proteins - metabolism Humans In Vitro Techniques Mesoporphyrins - blood Photochemotherapy Photosensitizing Agents - blood Protein Binding Rats Spectrometry, Fluorescence
Online-Zugang:	Volltext
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