Osteoprotegerin in gingival crevicular fluid under long-term continuous orthodontic force application
To investigate the level of osteoprotegerin (OPG) in gingival crevicular fluid (GCF) during tooth movement. Twelve patients (13-17 years of age) requiring canine distalization participated in the study. GCF sampling was done at baseline, 1 hour, 24 hours, 168 hours, 1 month, and 3 months from the di...
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| Veröffentlicht in: | The Angle orthodontist 2008-11, Vol.78 (6), p.988-993 |
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| container_title | The Angle orthodontist |
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| creator | Toygar, Hilal Uslu Kircelli, Beyza Hancioglu Bulut, Sule Sezgin, Nurzen Tasdelen, Bahar |
| description | To investigate the level of osteoprotegerin (OPG) in gingival crevicular fluid (GCF) during tooth movement.
Twelve patients (13-17 years of age) requiring canine distalization participated in the study. GCF sampling was done at baseline, 1 hour, 24 hours, 168 hours, 1 month, and 3 months from the distal sites of the test and with control teeth after the application of mechanical stress. OPG concentration was detected by enzyme-linked immunosorbent assay.
OPG concentrations in distal sites of the test teeth were decreased in a time-dependent manner. Decreasing is significant when compared with the baseline measurements (P = .038). Variability was detected in the levels of OPG concentration in the distal sites of the control tooth throughout the experimental period.
OPG is one of the key mediators responsible for alveolar bone remodeling during tooth movement. |
| doi_str_mv | 10.2319/100507-483.1 |
| format | Article |
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Twelve patients (13-17 years of age) requiring canine distalization participated in the study. GCF sampling was done at baseline, 1 hour, 24 hours, 168 hours, 1 month, and 3 months from the distal sites of the test and with control teeth after the application of mechanical stress. OPG concentration was detected by enzyme-linked immunosorbent assay.
OPG concentrations in distal sites of the test teeth were decreased in a time-dependent manner. Decreasing is significant when compared with the baseline measurements (P = .038). Variability was detected in the levels of OPG concentration in the distal sites of the control tooth throughout the experimental period.
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Twelve patients (13-17 years of age) requiring canine distalization participated in the study. GCF sampling was done at baseline, 1 hour, 24 hours, 168 hours, 1 month, and 3 months from the distal sites of the test and with control teeth after the application of mechanical stress. OPG concentration was detected by enzyme-linked immunosorbent assay.
OPG concentrations in distal sites of the test teeth were decreased in a time-dependent manner. Decreasing is significant when compared with the baseline measurements (P = .038). Variability was detected in the levels of OPG concentration in the distal sites of the control tooth throughout the experimental period.
OPG is one of the key mediators responsible for alveolar bone remodeling during tooth movement.</description><subject>Adolescent</subject><subject>Cuspid - pathology</subject><subject>Dentistry</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gingival Crevicular Fluid - chemistry</subject><subject>Humans</subject><subject>Male</subject><subject>Orthodontic Brackets</subject><subject>Orthodontic Wires</subject><subject>Osteoprotegerin - analysis</subject><subject>Stress, Mechanical</subject><subject>Time Factors</subject><subject>Tooth Movement Techniques - instrumentation</subject><issn>0003-3219</issn><issn>1945-7103</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LxDAQhoMo7rp68yw5ebJrPtqmOcriFyzsRc8lSSc10jY1SRf893bZBWHgZeDhZeZB6JaSNeNUPlJCCiKyvOJreoaWVOZFJijh52hJCOEZZ1Qu0FWM34SwosjZJVrQSuaCCblEsIsJ_Bh8ghaCG_A8rRtat1cdNgH2zkydCth2k2vwNDQQcOeHNksQemz8kNww-SliH9KXbw67wdYHA1iNY-eMSs4P1-jCqi7CzSlX6PPl-WPzlm13r--bp21mOBMpy3XBDBO2VKW1wgjNtSpKUmnJAGxhqMmFLnlDpeS0bKpKK21VZbSGSird8BW6P_bOD_1MEFPdu2ig69QA85F1KQXhksgZfDiCJvgYA9h6DK5X4bempD5orY9a61lrTWf87tQ76R6af_jkkf8BlJR19Q</recordid><startdate>200811</startdate><enddate>200811</enddate><creator>Toygar, Hilal Uslu</creator><creator>Kircelli, Beyza Hancioglu</creator><creator>Bulut, Sule</creator><creator>Sezgin, Nurzen</creator><creator>Tasdelen, Bahar</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200811</creationdate><title>Osteoprotegerin in gingival crevicular fluid under long-term continuous orthodontic force application</title><author>Toygar, Hilal Uslu ; Kircelli, Beyza Hancioglu ; Bulut, Sule ; Sezgin, Nurzen ; Tasdelen, Bahar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c327t-4b52c27f6a6ff7c7b3ba5608b92eef5c1c47b63d199316d88babfa8cbbe89abd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Cuspid - pathology</topic><topic>Dentistry</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gingival Crevicular Fluid - chemistry</topic><topic>Humans</topic><topic>Male</topic><topic>Orthodontic Brackets</topic><topic>Orthodontic Wires</topic><topic>Osteoprotegerin - analysis</topic><topic>Stress, Mechanical</topic><topic>Time Factors</topic><topic>Tooth Movement Techniques - instrumentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Toygar, Hilal Uslu</creatorcontrib><creatorcontrib>Kircelli, Beyza Hancioglu</creatorcontrib><creatorcontrib>Bulut, Sule</creatorcontrib><creatorcontrib>Sezgin, Nurzen</creatorcontrib><creatorcontrib>Tasdelen, Bahar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Angle orthodontist</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Toygar, Hilal Uslu</au><au>Kircelli, Beyza Hancioglu</au><au>Bulut, Sule</au><au>Sezgin, Nurzen</au><au>Tasdelen, Bahar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Osteoprotegerin in gingival crevicular fluid under long-term continuous orthodontic force application</atitle><jtitle>The Angle orthodontist</jtitle><addtitle>Angle Orthod</addtitle><date>2008-11</date><risdate>2008</risdate><volume>78</volume><issue>6</issue><spage>988</spage><epage>993</epage><pages>988-993</pages><issn>0003-3219</issn><eissn>1945-7103</eissn><abstract>To investigate the level of osteoprotegerin (OPG) in gingival crevicular fluid (GCF) during tooth movement.
Twelve patients (13-17 years of age) requiring canine distalization participated in the study. GCF sampling was done at baseline, 1 hour, 24 hours, 168 hours, 1 month, and 3 months from the distal sites of the test and with control teeth after the application of mechanical stress. OPG concentration was detected by enzyme-linked immunosorbent assay.
OPG concentrations in distal sites of the test teeth were decreased in a time-dependent manner. Decreasing is significant when compared with the baseline measurements (P = .038). Variability was detected in the levels of OPG concentration in the distal sites of the control tooth throughout the experimental period.
OPG is one of the key mediators responsible for alveolar bone remodeling during tooth movement.</abstract><cop>United States</cop><pmid>18947279</pmid><doi>10.2319/100507-483.1</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Cuspid - pathology Dentistry Female Follow-Up Studies Gingival Crevicular Fluid - chemistry Humans Male Orthodontic Brackets Orthodontic Wires Osteoprotegerin - analysis Stress, Mechanical Time Factors Tooth Movement Techniques - instrumentation |
| title | Osteoprotegerin in gingival crevicular fluid under long-term continuous orthodontic force application |
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