Improved liquid chromatography—Online radioactivity detection for metabolite profiling

If very-high-pressure liquid chromatography (VHPLC) is to replace conventional HPLC as the ultimate separation tool for metabolism studies in development, coupling it efficiently with online radioactivity detection (RAD) is needed. We describe the successful combination of VHPLC/RAD, facilitated by...

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Veröffentlicht in:	Journal of Chromatography A 2008-10, Vol.1209 (1-2), p.128-135
Hauptverfasser:	Cuyckens, Filip, Koppen, Valerie, Kembuegler, Rainer, Leclercq, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Carbon Radioisotopes Chromatography, High Pressure Liquid - methods Chromatography, Liquid - methods General pharmacology Medical sciences Metabolite profiling Online radioactivity detection Pharmacology. Drug treatments Radio-HPLC Radiometry - methods Reproducibility of Results UHPLC UPLC VHPLC
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