The Glucocorticoid Response Element II Is Functionally Homologous in Rat and Human Insulin-like Growth Factor-binding Protein-1 Promoters

In vivo, insulin-like growth factor-binding protein-1 (IGFBP-1) modulates the IGFs’ bioavailability and may contribute to their delivery to peripheral tissues. In rat and human hepatocytes, glucocorticoids stimulate IGFBP-1 gene transcription through homologous glucocorticoid response units (GRU)....

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Veröffentlicht in:The Journal of biological chemistry 1999-04, Vol.274 (17), p.11679-11686
Hauptverfasser: Schweizer-Groyer, G, Jibard, N, Neau, E, Fortin, D, Cadepond, F, Baulieu, E E, Groyer, A
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Sprache:eng
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