Monitoring of anaesthesia in neurophysiological experiments

Cortical activity can be substantially changed by the type of anaesthetic used, and by its dose level. For easy monitoring of depth of anaesthesia we describe the changes in electroencephalogram and electrocardiogram accompanying changes in depth of anaesthesia in the cat. Anaesthesia was induced by...

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Veröffentlicht in:Neuroreport 1999-03, Vol.10 (4), p.781-787
Hauptverfasser: Kral, A, Tillein, J, Hartmann, R, Klinke, R
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creator Kral, A
Tillein, J
Hartmann, R
Klinke, R
description Cortical activity can be substantially changed by the type of anaesthetic used, and by its dose level. For easy monitoring of depth of anaesthesia we describe the changes in electroencephalogram and electrocardiogram accompanying changes in depth of anaesthesia in the cat. Anaesthesia was induced by the volatile anaesthetic isoflurane. The high-frequency components (around 30 Hz) in the electroencephalogram disappear in deep anaesthesia. The electrocardiogram also shows substantial changes in contamination due to muscle fasciculations with anaesthesia level. Fasciculations appear as noise in the electrocardiogram. The amplitude of the electrical muscle activity contaminating the ECG can be easily used for the maintainance of a constant level of anaesthesia during a neurophysiological experiment.
doi_str_mv 10.1097/00001756-199903170-00022
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subjects Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Animals
Biological and medical sciences
Cats
Electrocardiography - drug effects
Electroencephalography - drug effects
Electrophysiology
General anesthesia. Technics. Complications. Neuromuscular blocking. Premedication. Surgical preparation. Sedation
Medical sciences
Muscle Relaxation - drug effects
Muscle, Skeletal - drug effects
Muscle, Skeletal - physiology
Neuromuscular Nondepolarizing Agents - pharmacology
Neurophysiology - methods
Pancuronium - pharmacology
Vestibulocochlear Nerve - drug effects
Vestibulocochlear Nerve - physiology
title Monitoring of anaesthesia in neurophysiological experiments
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