The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol

Through genome-wide association studies, we have recently identified seven novel loci that confer a substantial increase in risk for coronary artery disease (CAD). Elucidating the mechanisms by which these loci affect CAD risk could have important clinical utility. Here, we investigated whether thes...

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Veröffentlicht in:Journal of molecular medicine (Berlin, Germany) Germany), 2008-11, Vol.86 (11), p.1233-1241
Hauptverfasser: Samani, Nilesh J., Braund, Peter S., Erdmann, Jeanette, Götz, Anika, Tomaszewski, Maciej, Linsel-Nitschke, Patrick, Hajat, Cother, Mangino, Massimo, Hengstenberg, Christian, Stark, Klaus, Ziegler, Andreas, Caulfield, Mark, Burton, Paul R., Schunkert, Heribert, Tobin, Martin D.
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Sprache:eng
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