Microglia as mediators of inflammatory and degenerative diseases

Microglia are the principal immune cells in the central nervous system (CNS) and have a critical role in host defense against invading microorganisms and neoplastic cells. However, as with immune cells in other organs, microglia may play a dual role, amplifying the effects of inflammation and mediat...

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Veröffentlicht in:	Annual review of neuroscience 1999-01, Vol.22 (1), p.219-240
Hauptverfasser:	GONZALEZ-SCARANO, F, BALTUCH, G
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Alzheimer Disease - physiopathology Animals Biological and medical sciences Central Nervous System Diseases - physiopathology Fundamental and applied biological sciences. Psychology HIV Infections - physiopathology Human immunodeficiency virus 1 Humans Inflammation - physiopathology Isolated neuron and nerve. Neuroglia Microglia - physiology Multiple Sclerosis - physiopathology Nerve Degeneration - physiopathology Vertebrates: nervous system and sense organs
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