Phosphatidylinositol 3'-Kinase, But Not S6-Kinase, Is Required for Insulin-Like Growth Factor-I and IL-4 To Maintain Expression of Bcl-2 and Promote Survival of Myeloid Progenitors

Phosphatidylinositol 3'-kinase (PI 3-kinase) catalyzes the formation of 3' phosphoinositides and has been implicated in an intracellular signaling pathway that inhibits apoptosis in both neuronal and hemopoietic cells. Here, we investigated two potential downstream mediators of PI 3-kinase...

Ausführliche Beschreibung