Effects of different adjuvants on rotavirus antibody responses and protection in mice following intramuscular immunization with inactivated rotavirus

I.m. immunization of mice with inactivated rotavirus particles protects against subsequent infection. To optimize protection, the effects of different adjuvants (QS-21, QS-7, QUIL A, PCPP and RAS) with potential for human use were compared. Twenty-eight days after i.m. immunization with 20 μg of pur...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 1999-03, Vol.17 (11), p.1573-1580
Hauptverfasser:	McNeal, Monica M, Rae, Mary N, Ward, Richard L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic Animals Antibodies, Viral - biosynthesis Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Injections, Intramuscular Intramuscular immunization Mice Mice, Inbred BALB C Microbiology Rotavirus Rotavirus - immunology Rotavirus Infections - prevention & control Saponins - immunology Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Inactivated - administration & dosage Vaccines, Inactivated - immunology Viral Vaccines - administration & dosage Viral Vaccines - immunology Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!